Pre_GI: BLASTP Hits

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Query: NC_016768:2764000:2775550 Mycobacterium tuberculosis KZN 4207 chromosome, complete genome

Start: 2775550, End: 2779776, Length: 4227

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_020133:4911044:492389649238964924432537Mycobacterium liflandii 128FXT, complete genome3e-1895.5
NC_020133:5020500:503853150385315039034504Mycobacterium liflandii 128FXT, complete genome3e-1378.6
NC_019950:2830682:2830682283068228327662085Mycobacterium canettii CIPT 140060008 complete genomeConserved protein of unknown function, PE-PGRS family protein2e-1792.4
NC_019950:2830682:2833096283309628369803885Mycobacterium canettii CIPT 140060008 complete genomeConserved protein of unknown function, PE-PGRS family protein2e-1689.4
NC_019950:2830682:2840852284085228458344983Mycobacterium canettii CIPT 140060008 complete genomeConserved protein of unknown function, PE-PGRS family protein PE_PGRS543e-25118
NC_016768:3296478:3315569331556933183702802Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein3e-21105
NC_016768:3296478:3312205331220533136231419Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein5e-1894.4
NC_016768:830000:833994833994834512519Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein1e-0863.2
NC_016768:2764000:2771960277196027741762217Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein5e-49197
NC_002945:2757821:2771504277150427730331530Mycobacterium bovis AF2122/97, complete genomehypothetical protein8e-25117
NC_002945:2757821:276356627635662764186621Mycobacterium bovis AF2122/97, complete genomehypothetical protein2e-1792.4
NC_017026:2786000:2788929278892927910132085Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein2e-1792.4
NC_020133:4911044:4934271493427149360371767Mycobacterium liflandii 128FXT, complete genomePE family protein2e-1069.3
NC_010612:5301135:5321829532182953235951767Mycobacterium marinum M, complete genomePE family protein2e-1069.7
NC_017904:4742775:475137047513704751669300Mycobacterium sp. MOTT36Y chromosome, complete genomePE family protein2e-0862.4
NC_016804:831500:834734834734835252519Mycobacterium bovis BCG str. Mexico chromosome, complete genomePE PGRS family protein1e-0863.2
NC_016804:3753243:3767225376722537694772253Mycobacterium bovis BCG str. Mexico chromosome, complete genomePE PGRS family protein4e-22108
NC_009565:1629780:1640600164060016428132214Mycobacterium tuberculosis F11, complete genomePE-PGRS family protein8e-49196
NC_009565:1629780:1635000163500016392234224Mycobacterium tuberculosis F11, complete genomePE-PGRS family protein5e-47191
NC_012207:2747599:2761378276137827628051428Mycobacterium bovis BCG str. Tokyo 172, complete genomePE-PGRS family protein5e-25117
NC_000962:2791019:2801254280125428062364983Mycobacterium tuberculosis H37Rv, complete genomePE-PGRS FAMILY PROTEIN8e-25117
NC_020133:942375:9423759423759441201746Mycobacterium liflandii 128FXT, complete genomePE-PGRS family protein2e-24116
NC_017026:3894000:3909070390907039103891320Mycobacterium tuberculosis RGTB327 chromosome, complete genomePE-PGRS family protein4e-22108
NC_009565:3793976:3812770381277038149652196Mycobacterium tuberculosis F11, complete genomePE-PGRS family protein4e-22108
NC_012207:3766978:3785773378577337880252253Mycobacterium bovis BCG str. Tokyo 172, complete genomePE-PGRS family protein4e-22108
NC_010612:6385520:6388395638839563956937299Mycobacterium marinum M, complete genomePE-PGRS family protein1e-20103
NC_020133:5020500:5028630502863050313532724Mycobacterium liflandii 128FXT, complete genomePE-PGRS family protein3e-1998.6
NC_008769:1125567:1125567112556711269401374Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomePE-PGRS family protein2e-1895.5
NC_020133:5965500:5972633597263359781105478Mycobacterium liflandii 128FXT, complete genomePE-PGRS family protein3e-1895.5
NC_008769:2754828:2759609275960927611921584Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomePE-PGRS family protein9e-1893.6
NC_009565:2806000:2809407280940728107021296Mycobacterium tuberculosis F11, complete genomePE-PGRS family protein2e-1792.8
NC_015848:2859145:2861559286155928654673909Mycobacterium canettii CIPT 140010059, complete genomePE-PGRS family protein2e-1689.4
NC_010612:4400260:4401186440118644032372052Mycobacterium marinum M, complete genomePE-PGRS family protein3e-1378.6
NC_010612:957786:9627049627049690126309Mycobacterium marinum M, complete genomePE-PGRS family protein5e-1274.7
NC_016804:2560000:2574129257412925753701242Mycobacterium bovis BCG str. Mexico chromosome, complete genomePE-PGRS family protein1e-0966.6
NC_012207:831030:834815834815835333519Mycobacterium bovis BCG str. Tokyo 172, complete genomePE-PGRS family protein1e-0863.2
NC_010612:6113155:6113155611315561150561902Mycobacterium marinum M, complete genomePE-PGRS family protein2e-0862.8
NC_002945:1621765:1632588163258816349752388Mycobacterium bovis AF2122/97, complete genomePE-PGRS family protein2e-47191
NC_016804:2735897:2747970274797027493971428Mycobacterium bovis BCG str. Mexico chromosome, complete genomePE-PGRS family protein5e-25117
NC_010612:5626259:5639613563961356433683756Mycobacterium marinum M, complete genomePE-PGRS family protein2e-24116
NC_009525:3794000:3810776381077638125241749Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein3e-22108
NC_000962:3781501:3801653380165338038482196Mycobacterium tuberculosis H37Rv, complete genomePE-PGRS FAMILY PROTEIN4e-22108
NC_008769:3769065:3787860378786037901122253Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomePE-PGRS family protein4e-22108
NC_020133:4841932:4857957485795748599241968Mycobacterium liflandii 128FXT, complete genomePE-PGRS family protein3e-21105
NC_009525:3933567:3939682393968239443194638Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein5e-21104
NC_010612:6113155:6120939612093961252944356Mycobacterium marinum M, complete genomePE-PGRS family protein2e-1999.8
NC_016804:1095846:1095846109584610972191374Mycobacterium bovis BCG str. Mexico chromosome, complete genomePE-PGRS family protein2e-1895.5
NC_012943:3299744:3315516331551633168891374Mycobacterium tuberculosis KZN 1435 chromosome, complete genomePE-PGRS family protein5e-1894.7
NC_016804:2735897:2738974273897427405571584Mycobacterium bovis BCG str. Mexico chromosome, complete genomePE-PGRS family protein9e-1893.6
NC_012943:3299744:3317611331761133186181008Mycobacterium tuberculosis KZN 1435 chromosome, complete genomePE-PGRS family protein1e-1793.6
NC_015848:2859145:2859145285914528612292085Mycobacterium canettii CIPT 140010059, complete genomePE-PGRS family protein2e-1792.4
NC_009525:2802987:2807269280726928093532085Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein2e-1792.4
NC_017026:1095753:1095753109575310971291377Mycobacterium tuberculosis RGTB327 chromosome, complete genomePE-PGRS family protein2e-1276.3
NC_002945:831029:834814834814835332519Mycobacterium bovis AF2122/97, complete genomePE-PGRS family protein1e-0863.2
NC_009525:3933567:3935246393524639393914146Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein2e-0655.8
NC_002945:1621765:1626985162698516312114227Mycobacterium bovis AF2122/97, complete genomePE-PGRS family protein2e-47192
NC_015848:2859145:2869315286931528742974983Mycobacterium canettii CIPT 140010059, complete genomePE-PGRS family protein7e-25117
NC_009565:2806000:281872728187272819545819Mycobacterium tuberculosis F11, complete genomePE-PGRS family protein1e-23112
NC_012943:3777371:3796165379616537983602196Mycobacterium tuberculosis KZN 1435 chromosome, complete genomePE-PGRS family protein4e-22108
NC_002945:3735141:3753936375393637561852250Mycobacterium bovis AF2122/97, complete genomePE-PGRS family protein4e-22108
NC_017026:3754000:377091037709103771389480Mycobacterium tuberculosis RGTB327 chromosome, complete genomePE-PGRS family protein7e-22107
NC_017026:3894000:3915130391513039161881059Mycobacterium tuberculosis RGTB327 chromosome, complete genomePE-PGRS family protein4e-21105
NC_010612:5301135:5307272530727253131965925Mycobacterium marinum M, complete genomePE-PGRS family protein8e-1997.1
NC_002945:1095337:1095529109552910969021374Mycobacterium bovis AF2122/97, complete genomePE-PGRS family protein2e-1895.5
NC_000962:1095078:1095078109507810964511374Mycobacterium tuberculosis H37Rv, complete genomePE-PGRS FAMILY PROTEIN3e-1895.1
NC_016768:3296478:3314345331434533153521008Mycobacterium tuberculosis KZN 4207 chromosome, complete genomePE-PGRS family protein1e-1793.6
NC_017026:3894000:3900446390044639021281683Mycobacterium tuberculosis RGTB327 chromosome, complete genomePE-PGRS family protein7e-1687.4
NC_010612:5403000:5418899541889954214122514Mycobacterium marinum M, complete genomePE-PGRS family protein2e-1276.3
NC_017026:829444:833487833487834005519Mycobacterium tuberculosis RGTB327 chromosome, complete genomePE-PGRS family protein1e-0863.2
NC_009525:830513:834296834296834814519Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein1e-0863.2
NC_008769:860670:864455864455864973519Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomePE-PGRS family protein1e-0863.2
NC_020133:1443934:1448452144845214496511200Mycobacterium liflandii 128FXT, complete genomePE-PGRS family protein4e-0861.6
NC_015848:1647523:1659310165931016623303021Mycobacterium canettii CIPT 140010059, complete genomePE-PGRS family protein2e-47192
NC_015848:1647523:1653707165370716579334227Mycobacterium canettii CIPT 140010059, complete genomePE-PGRS family protein2e-41172
NC_008769:2754828:2768605276860527700321428Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomePE-PGRS family protein5e-25117
NC_009525:2802987:2813222281322228182044983Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein8e-25117
NC_009525:3933567:3949108394910839512612154Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein7e-24114
NC_016768:3774105:3792899379289937950942196Mycobacterium tuberculosis KZN 4207 chromosome, complete genomePE-PGRS family protein4e-22108
NC_012943:3299744:3318835331883533216362802Mycobacterium tuberculosis KZN 1435 chromosome, complete genomePE-PGRS family protein3e-21105
NC_009525:3933567:3955294395529439589293636Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein1e-20103
NC_010612:5403000:5410995541099554137272733Mycobacterium marinum M, complete genomePE-PGRS family protein3e-1998.6
NC_012207:1097228:1097228109722810986011374Mycobacterium bovis BCG str. Tokyo 172, complete genomePE-PGRS family protein2e-1895.5
NC_009525:1096386:1096386109638610977591374Mycobacterium tuberculosis H37Ra, complete genomePE-PGRS family protein3e-1895.1
NC_009565:1098847:1098847109884711002201374Mycobacterium tuberculosis F11, complete genomePE-PGRS family protein8e-1894
NC_012207:2747599:2752380275238027539631584Mycobacterium bovis BCG str. Tokyo 172, complete genomePE-PGRS family protein9e-1893.6
NC_000962:2791019:2795301279530127973852085Mycobacterium tuberculosis H37Rv, complete genomePE-PGRS FAMILY PROTEIN2e-1792.4
NC_010612:2215724:2224183222418322298075625Mycobacterium marinum M, complete genomePE-PGRS family protein3e-1378.6
NC_020133:1443934:1451027145102714522381212Mycobacterium liflandii 128FXT, complete genomePE-PGRS family protein4e-1171.6
NC_012207:2573562:2587536258753625887771242Mycobacterium bovis BCG str. Tokyo 172, complete genomePE-PGRS family protein1e-0966.6
NC_012943:830000:833990833990834508519Mycobacterium tuberculosis KZN 1435 chromosome, complete genomePE-PGRS family protein1e-0863.2
NC_009565:833076:836859836859837377519Mycobacterium tuberculosis F11, complete genomePE-PGRS family protein1e-0863.2
NC_010612:5403000:5408042540804254107742733Mycobacterium marinum M, complete genomePE-PGRS family protein, PE_PGRS9_31e-1999.8
NC_002755:2788000:2796742279674228017394998Mycobacterium tuberculosis CDC1551, complete genomePE_PGRS family protein8e-25117
NC_002755:831397:835179835179835697519Mycobacterium tuberculosis CDC1551, complete genomePE_PGRS family protein1e-0863.2
NC_002755:1095105:1095105109510510965351431Mycobacterium tuberculosis CDC1551, complete genomePE_PGRS family protein9e-1893.6
NC_002755:2788000:2790789279078927928732085Mycobacterium tuberculosis CDC1551, complete genomePE_PGRS family protein2e-1792.4
NC_002755:3773734:3792396379239637947232328Mycobacterium tuberculosis CDC1551, complete genomePE_PGRS family protein5e-22107