Pre_GI: BLASTP Hits

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Query: NC_016582:9459566:9475177 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Start: 9475177, End: 9475647, Length: 471

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010572:802269:820891820891821358468Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein2e-51201
NC_008278:874015:896021896021896683663Frankia alni ACN14a, complete genomehypothetical protein6e-41166
NC_006361:1547034:157009715700971570717621Nocardia farcinica IFM 10152, complete genomehypothetical protein5e-23106
NC_008699:3896816:391365139136513914028378Nocardioides sp. JS614, complete genomehypothetical protein9e-1992.4
NC_015859:1099919:110494111049411105504564Corynebacterium variabile DSM 44702 chromosome, complete genomehypothetical protein6e-0960.1