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Query: NC_016582:8243727:8254015 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Start: 8254015, End: 8254536, Length: 522

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016582:8711199:872183587218358722347513Streptomyces bingchenggensis BCW-1 chromosome, complete genomeputative acetyltransferase3e-50197
NC_010572:4505428:451480045148004515327528Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative acetyltransferase4e-38157
NC_016111:1766010:181952118195211820063543Streptomyces cattleya NRRL 8057, complete genomeacetyltransferase1e-36152
NC_003155:210240:220848220848221402555Streptomyces avermitilis MA-4680, complete genomeacetyltransferase2e-28124
NC_014391:4644500:465458046545804655131552Micromonospora aurantiaca ATCC 27029 chromosome, complete genomeGCN5-related N-acetyltransferase6e-1993.2
NC_016582:10104458:101317841013178410132323540Streptomyces bingchenggensis BCW-1 chromosome, complete genomeacetyltransferase1e-1789.4
NC_016113:887582:895027895027895566540Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequenceAcetyltransferase1e-1789
NC_006361:1547034:155130015513001551854555Nocardia farcinica IFM 10152, complete genomeputative acetyltransferase4e-1580.9
NC_016887:4343830:435156343515634352159597Nocardia cyriacigeorgica GUH-2, complete genomeputative GCN5-related acetyltransferase4e-1270.9