Pre_GI: BLASTP Hits

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Query: NC_016516:2380131:2393664 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Start: 2393664, End: 2394689, Length: 1026

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014039:2386347:2399786239978624009041119Propionibacterium acnes SK137 chromosome, complete genomeputative adenosine deaminase9e-177619
NC_016512:2388612:2402162240216224031691008Propionibacterium acnes TypeIA2 P.acn17 chromosome, completeadenosine deaminase5e-174610
NC_016511:2389273:2402823240282324038301008Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeadenosine deaminase5e-174610
NC_020133:1443934:1463843146384314649311089Mycobacterium liflandii 128FXT, complete genomeadenosine deaminase Add1e-55217
NC_008529:1265958:127536012753601276352993Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365, completeAdenosine deaminase3e-36152
NC_008054:1255219:126237712623771263369993Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, completeAdenosine deaminase9e-36150
NC_009706:830461:8304618304618315071047Clostridium kluyveri DSM 555 chromosome, complete genomeadenosine deaminase9e-35147
NC_011837:830436:8304368304368314821047Clostridium kluyveri NBRC 12016, complete genomeadenosine deaminase9e-35147
NC_014833:1539678:1541512154151215425221011Ruminococcus albus 7 chromosome, complete genomeadenosine deaminase2e-33142
NC_014328:3120145:3132460313246031334851026Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeadenosine deaminase7e-33141
NC_016011:2875747:287475828747582875750993Listeria ivanovii subsp. ivanovii PAM 55, complete genomeputative adenosine deaminase2e-32140
NC_009778:1902995:1919449191944919204801032Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein1e-29130
NC_014121:2330451:2352341235234123533421002Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeadenosine deaminase7e-29128
NC_013515:1321336:132921413292141330212999Streptobacillus moniliformis DSM 12112, complete genomeadenosine deaminase2e-26120
NC_007350:2460134:246320224632022464176975Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305,putative adenosine deaminase2e-26119
NC_013928:797714:8014608014608024761017Streptococcus mutans NN2025, complete genomeadenosine deaminase6e-26118
NC_016745:546249:5662615662615672651005Oceanimonas sp. GK1 chromosome, complete genomeadenosine deaminase2e-23110
NC_013714:1521404:1526390152639015274151026Bifidobacterium dentium Bd1, complete genomeadenosine deaminase9e-23107
NC_007643:889755:9031449031449041481005Rhodospirillum rubrum ATCC 11170, complete genomeAdenosine deaminase1e-22107
NC_012815:1092795:1095506109550610965311026Bifidobacterium animalis subsp. lactis DSM 10140, complete genomeadenosine deaminase2e-21103
NC_012814:1092860:1095571109557110965961026Bifidobacterium animalis subsp. lactis Bl-04, complete genomeadenosine deaminase2e-21103
NC_011835:1819707:1822418182241818234431026Bifidobacterium animalis subsp. lactis AD011 chromosome, completeadenosine deaminase2e-21103
NC_017216:1092751:1095462109546210964871026Bifidobacterium animalis subsp. lactis BLC1, complete genomeadenosine deaminase2e-21103
NC_017217:1092916:1095627109562710966521026Bifidobacterium animalis subsp. lactis V9 chromosome, completeadenosine deaminase2e-21103
NC_009480:739395:7431607431607441611002Clavibacter michiganensis subsp. michiganensis NCPPB 382, completeputative adenosine deaminase5e-21102
NC_013235:5127148:5127148512714851282301083Nakamurella multipartita DSM 44233, complete genomeadenosine deaminase6e-21101
NC_018524:4988810:503648150364815037464984Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomeadenosine deaminase3e-2099.4
NC_016109:3591401:3610420361042036114481029Kitasatospora setae KM-6054, complete genomeputative adenosine deaminase5e-2098.6
NC_017171:1331794:1359703135970313607431041Acinetobacter baumannii MDR-ZJ06 chromosome, complete genomeadenosine deaminase9e-2097.8
NC_014210:2372813:239305223930522394041990Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,adenosine deaminase2e-1996.7
NC_015957:639774:6618656618656628961032Streptomyces violaceusniger Tu 4113 chromosome, complete genomeadenosine deaminase4e-1995.9
NC_008825:846916:8476928476928487651074Methylibium petroleiphilum PM1, complete genomeadenosine deaminase4e-1995.9
NC_007963:2232000:2236177223617722372021026Chromohalobacter salexigens DSM 3043, complete genomeadenosine deaminase7e-1995.1
NC_011761:684969:7001427001427011851044Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completeadenosine deaminase2e-1893.6
NC_011206:863987:8791608791608802031044Acidithiobacillus ferrooxidans ATCC 53993, complete genomeadenosine deaminase2e-1893.6
NC_014666:7222000:7228114722811472291841071Frankia sp. EuI1c chromosome, complete genomeadenosine deaminase3e-1892.8
NC_021177:4912982:4915456491545649164871032Streptomyces fulvissimus DSM 40593, complete genomeAdenosine deaminase6e-1892
NC_010572:3363830:3381783338178333828141032Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative adenosine deaminase7e-1788.2
NC_003155:5957657:5961860596186059628881029Streptomyces avermitilis MA-4680, complete genomeadenosine deaminase1e-1687.8
NC_003888:5042283:5068592506859250696231032Streptomyces coelicolor A3(2), complete genomeadenosine deaminase6e-1685.1
NC_013929:4186840:4201945420194542029881044Streptomyces scabiei 87.22 chromosome, complete genomeadenosine deaminase6e-1582
NC_013947:4363250:437359243735924374581990Stackebrandtia nassauensis DSM 44728 chromosome, complete genomeAdenosine deaminase3e-1479.7
NC_018750:4688968:4691352469135246923741023Streptomyces venezuelae ATCC 10712, complete genomeAdenosine deaminase6e-1478.6
NC_016111:3769818:3771079377107937720921014Streptomyces cattleya NRRL 8057, complete genomeadenosine deaminase8e-1478.2
NC_017030:6297351:631107363110736312065993Corallococcus coralloides DSM 2259 chromosome, complete genomeadenosine/AMP deaminase family protein2e-1377.4
NC_009664:1569335:1609121160912116101971077Kineococcus radiotolerans SRS30216, complete genomeadenosine deaminase4e-1375.9
NC_010623:72500:8089580895819081014Burkholderia phymatum STM815 chromosome 2, complete sequenceadenosine deaminase3e-1169.7
NC_010623:72500:9439794397954221026Burkholderia phymatum STM815 chromosome 2, complete sequenceadenosine deaminase2e-0963.5
NC_014311:3076519:3097177309717730982261050Ralstonia solanacearum PSI07 chromosome, complete genomeadenosine deaminase (add)4e-0962.4
NC_013947:4363250:436325043632504364242993Stackebrandtia nassauensis DSM 44728 chromosome, complete genomeadenosine deaminase3e-0859.7
NC_014666:1969602:198638019863801987009630Frankia sp. EuI1c chromosome, complete genomeadenosine/AMP deaminase1e-0654.3