Pre_GI: BLASTP Hits

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Query: NC_016516:2380131:2388896 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Start: 2388896, End: 2390107, Length: 1212

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_020133:902000:9149019149019162201320Mycobacterium liflandii 128FXT, complete genomeconserved lipoprotein LprQ3e-44179
NC_010612:957786:9711169711169725041389Mycobacterium marinum M, complete genomeconserved lipoprotein LprQ4e-44179
NC_014039:2386347:2395111239511123963221212Propionibacterium acnes SK137 chromosome, complete genomeErfK/YbiS/YcfS/YnhG0759
NC_015434:1313979:1313979131397913152921314Verrucosispora maris AB-18-032 chromosome, complete genomeerfk/ybis/ycfs/ynhg family protein6e-55215
NC_013441:2761459:2767778276777827689471170Gordonia bronchialis DSM 43247, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-43176
NC_009077:4747922:4761685476168547627221038Mycobacterium sp. JLS, complete genomeErfK/YbiS/YcfS/YnhG family protein3e-42172
NC_013441:2788806:2810164281016428114111248Gordonia bronchialis DSM 43247, complete genomeErfK/YbiS/YcfS/YnhG family protein8e-41168
NC_009338:2925286:2956301295630129575661266Mycobacterium gilvum PYR-GCK chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-38160
NC_014168:2575799:259470025947002595554855Segniliparus rotundus DSM 44985 chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-35150
NC_015953:1756493:1764232176423217654881257Streptomyces sp. SirexAA-E chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-49197
NC_015957:336500:3501643501643514231260Streptomyces violaceusniger Tu 4113 chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein1e-46187
NC_009077:4747922:4757958475795847591781221Mycobacterium sp. JLS, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-43177
NC_013441:2842134:2850387285038728516341248Gordonia bronchialis DSM 43247, complete genomeErfK/YbiS/YcfS/YnhG family protein3e-41169
NC_013093:1157476:1171277117127711724791203Actinosynnema mirum DSM 43827, complete genomeErfK/YbiS/YcfS/YnhG family protein9e-37154
NC_009664:3718927:3729570372957037307901221Kineococcus radiotolerans SRS30216, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-57223
NC_013510:3640776:3642789364278936440841296Thermomonospora curvata DSM 43183, complete genomeErfK/YbiS/YcfS/YnhG family protein6e-54211
NC_014210:3763940:3765091376509137663861296Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,ErfK/YbiS/YcfS/YnhG family protein9e-47187
NC_008705:1557711:1580119158011915813391221Mycobacterium sp. KMS, complete genomeErfK/YbiS/YcfS/YnhG family protein1e-43177
NC_013510:3032114:3048835304883530500011167Thermomonospora curvata DSM 43183, complete genomeErfK/YbiS/YcfS/YnhG family protein1e-41171
NC_008726:3915979:392550239255023926458957Mycobacterium vanbaalenii PYR-1, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-40167
NC_008726:3947917:3956675395667539579401266Mycobacterium vanbaalenii PYR-1, complete genomeErfK/YbiS/YcfS/YnhG family protein5e-37155
NC_013510:3032114:3047412304741230486471236Thermomonospora curvata DSM 43183, complete genomeErfK/YbiS/YcfS/YnhG family protein1e-32140
NC_013757:1499643:1512161151216115133811221Geodermatophilus obscurus DSM 43160, complete genomeErfK/YbiS/YcfS/YnhG family protein7e-55214
NC_015434:1313979:1315418131541813164911074Verrucosispora maris AB-18-032 chromosome, complete genomeerfk/ybis/ycfs/ynhg family protein7e-48191
NC_009077:4774499:4781580478158047828031224Mycobacterium sp. JLS, complete genomeErfK/YbiS/YcfS/YnhG family protein4e-43175
NC_009077:3851203:3854584385458438558041221Mycobacterium sp. JLS, complete genomeErfK/YbiS/YcfS/YnhG family protein4e-42172
NC_019673:1275627:1297536129753612987471212Saccharothrix espanaensis DSM 44229 complete genomeErfK/YbiS/YcfS/YnhG family protein3e-37156
NC_013131:9976929:1000210510002105100031811077Catenulispora acidiphila DSM 44928, complete genomeErfK/YbiS/YcfS/YnhG family protein7e-33141
NC_013131:10322152:103284451032844510329101657Catenulispora acidiphila DSM 44928, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-0963.5
NC_016511:2389273:2398037239803723992481212Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeErfK/YbiS/YcfS/YnhG protein0758
NC_002944:4254011:425960642596064260421816Mycobacterium avium subsp. paratuberculosis K-10, complete genomehypothetical protein2e-26120
NC_014814:5422972:5445253544525354464761224Mycobacterium sp. Spyr1 chromosome, complete genomehypothetical protein2e-42173
NC_006361:3615322:363299036329903633751762Nocardia farcinica IFM 10152, complete genomehypothetical protein2e-31137
NC_018524:2423016:2428136242813624294221287Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomeL,D-transpeptidase catalytic domain protein6e-43175
NC_021177:1922930:1933670193367019350371368Streptomyces fulvissimus DSM 40593, complete genomeLipoprotein7e-53208
NC_007164:622000:6223796223796235871209Corynebacterium jeikeium K411, complete genomeputative lipoprotein1e-39164
NC_012704:1641684:1660980166098016621821203Corynebacterium kroppenstedtii DSM 44385, complete genomeputative lipoprotein1e-40167
NC_010572:6293417:6303157630315763044101254Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative secreted protein4e-49196
NC_018750:2005229:2016218201621820174741257Streptomyces venezuelae ATCC 10712, complete genomeputative secreted protein4e-50199
NC_016512:2388612:2397376239737623985871212Propionibacterium acnes TypeIA2 P.acn17 chromosome, completesecreted lipoprotein0759
NC_003888:2305901:2314942231494223162161275Streptomyces coelicolor A3(2), complete genomesecreted protein3e-55216
NC_017186:7822448:7829487782948778305301044Amycolatopsis mediterranei S699 chromosome, complete genomeYkud domain-containing protein1e-51204
NC_014318:7821227:7829441782944178304841044Amycolatopsis mediterranei U32 chromosome, complete genomeYkud domain-containing protein1e-51204