Pre_GI: BLASTP Hits

Some Help

Query: NC_016516:2380131:2388541 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Start: 2388541, End: 2388672, Length: 132

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016512:2388612:239702123970212397152132Propionibacterium acnes TypeIA2 P.acn17 chromosome, completehypothetical protein3e-0857
NC_016511:2389273:239768223976822397813132Propionibacterium acnes TypeIA2 P.acn31 chromosome, completehypothetical protein3e-0857
NC_014039:2386347:239475623947562394887132Propionibacterium acnes SK137 chromosome, complete genomehypothetical protein3e-0857