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Query: NC_016512:2506898 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Start: 2506898, End: 2533499, Length: 26602

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_014039:2479500*2479500250599926500Propionibacterium acnes SK137 chromosome, complete genome052280BLASTN svgBLASTP svg
NC_006085:2544421*2544421257099926579Propionibacterium acnes KPA171202, complete genome052280BLASTN svgBLASTP svg
NC_013510:1*11865618656Thermomonospora curvata DSM 43183, complete genome9e-1693.7BLASTN svgBLASTP svg
NC_015312:1*12465124651Pseudonocardia dioxanivorans CB1190 chromosome, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_003888:4251867*4251867430640654540Streptomyces coelicolor A3(2), complete genome1e-1489.7BLASTN svgBLASTP svg
NC_013521:4240468*4240468426799927532Sanguibacter keddieii DSM 10542, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_014151:4106624*4106624413399927376Cellulomonas flavigena DSM 20109 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_014830:4012999*4012999403999927001Intrasporangium calvum DSM 43043 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_007333:111820218202Thermobifida fusca YX, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_007333:3626510*3626510365399927490Thermobifida fusca YX, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_008711:4579997*4579997460549925503Arthrobacter aurescens TC1, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013595:10329633*103296331035599926367Streptosporangium roseum DSM 43021, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_015564:4727630*4727630475399926370Amycolicicoccus subflavus DQS3-9A1 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_015953:3684065*3684065371159927535Streptomyces sp. SirexAA-E chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_018531:4718904*4718904474449925596Arthrobacter sp. Rue61a chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_018750:3964784*3964784398396119178Streptomyces venezuelae ATCC 10712, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_007164:2446879*2446879247349926621Corynebacterium jeikeium K411, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_008541:4679022*4679022470999930978Arthrobacter sp. FB24 chromosome 1, complete sequence5e-0867.9BLASTN svgBLASTP svg
NC_015145:4232283*4232283426249930217Arthrobacter phenanthrenivorans Sphe3 chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_008578:2431074*2431074245799926926Acidothermus cellulolyticus 11B, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_015067:2371428*2371428239399922572Bifidobacterium longum subsp. longum JCM 1217, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_014210:5752651*5752651577999927349Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,3e-0661.9BLASTN svgBLASTP svg
NC_010816:1660066*1660066168402823963Bifidobacterium longum DJO10A, complete genome3e-0661.9BLASTN svgBLASTP svg