Some Help

Query: NC_016512:305240:306603 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Start: 306603, End: 307592, Length: 990

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016627:2524307:254854625485462549505960Clostridium clariflavum DSM 19732 chromosome, complete genomeacetyl esterase6e-36151
NC_019970:929666:944550944550945506957Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeacetyl esterase (deacetylase)6e-28124
NC_014150:1423758:143993814399381440918981Brachyspira murdochii DSM 12563 chromosome, complete genomeAcetyl xylan esterase2e-55216
NC_015690:6595395:662412366241236625082960Paenibacillus mucilaginosus KNP414 chromosome, complete genomeacetyl xylan esterase7e-28124
NC_016582:11820671:118624701186247011863453984Streptomyces bingchenggensis BCW-1 chromosome, complete genomeAcetyl xylan esterase3e-59229
NC_009012:3591687:359784435978443598806963Clostridium thermocellum ATCC 27405, complete genomeAcetyl xylan esterase1e-36154
NC_010571:2943369:2971032297103229723961365Opitutus terrae PB90-1, complete genomeAcetyl xylan esterase2e-1067
NC_013174:2564979:257173325717332572662930Jonesia denitrificans DSM 20603, complete genomeAcetyl xylan esterase3e-34145
NC_017243:2955597:295559729555972956577981Brachyspira intermedia PWS/A chromosome, complete genomeacetyl xylan esterase, AXE1 family4e-53208
NC_014410:989698:100357810035781004534957Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,Cephalosporin-C deacetylase4e-28125
NC_015555:1792242:179562017956201796582963Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeCephalosporin-C deacetylase1e-25117
NC_021064:2001786:200178620017862002775990Propionibacterium avidum 44067, complete genomeputative acetyl xylan esterase4e-175613
NC_007333:1677406:1690536169053616917951260Thermobifida fusca YX, complete genomesimilar to Acetyl esterase (deacetylase)1e-48194