Pre_GI: BLASTP Hits

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Query: NC_016512:2388612:2407201 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Start: 2407201, End: 2408622, Length: 1422

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:2380131:2398721239872124001421422Propionibacterium acnes TypeIA2 P.acn33 chromosome, completethreonine synthase / cystathionine beta-synthase0973
NC_016511:2389273:2407863240786324092841422Propionibacterium acnes TypeIA2 P.acn31 chromosome, completethreonine synthase / cystathionine beta-synthase0973
NC_014039:2386347:2404937240493724063581422Propionibacterium acnes SK137 chromosome, complete genome2-amino-4-ketopentanoate thiolase, beta subunit0971
NC_011899:2286884:2290850229085022922561407Halothermothrix orenii H 168, complete genomeCysteine synthase1e-176619
NC_010718:1229355:1236299123629912377201422Natranaerobius thermophilus JW/NM-WN-LF, complete genomePyridoxal-5'-phosphate-dependent protein beta subunit1e-166586
NC_016751:1604048:1611624161162416130361413Marinitoga piezophila KA3 chromosome, complete genomecysteine synthase1e-165583
NC_009718:1771500:1791191179119117926181428Fervidobacterium nodosum Rt17-B1, complete genomepyridoxal-5'-phosphate-dependent protein beta subunit2e-164579
NC_010003:1242846:1252245125224512536631419Petrotoga mobilis SJ95, complete genomePyridoxal-5'-phosphate-dependent protein beta subunit9e-156550
NC_003413:1107965:1125994112599411271451152Pyrococcus furiosus DSM 3638, complete genomethreonine synthase3e-1067
NC_014960:1697818:1734618173461817357361119Anaerolinea thermophila UNI-1, complete genomethreonine synthase1e-0861.2
NC_017093:835260:8352608352608366181359Actinoplanes missouriensis 431, complete genomeputative cystathionine beta-synthase3e-0860.5
NC_014328:4387303:4387303438730343885621260Clostridium ljungdahlii ATCC 49587 chromosome, complete genomethreonine synthase4e-0860.1
NC_012988:32996:5312353123543641242Methylobacterium extorquens DM4, complete genometryptophan synthase, beta protein4e-0860.1
NC_014804:341663:3434283434283446031176Thermococcus barophilus MP chromosome, complete genomethreonine synthase4e-0860.1
NC_011757:97281:1129221129221141631242Methylobacterium chloromethanicum CM4, complete genometryptophan synthase, beta subunit4e-0859.7
NC_008054:1255219:125769512576951258618924Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, completeCysteine synthase6e-0859.3
NC_014297:1282302:1282302128230212834501149Halalkalicoccus jeotgali B3 chromosome, complete genomethreonine synthase7e-0859.3
NC_003901:357394:3789663789663801831218Methanosarcina mazei Go1, complete genomethreonine synthase7e-0859.3
NC_012883:1421644:1443086144308614442581173Thermococcus sibiricus MM 739, complete genomeThreonine synthase7e-0859.3
NC_014654:2311818:2325742232574223269891248Halanaerobium sp. 'sapolanicus' chromosome, complete genomethreonine synthase7e-0858.9
NC_015846:1065692:1070554107055410715881035Capnocytophaga canimorsus Cc5 chromosome, complete genomebeta-thionase9e-0858.5
NC_010382:3783879:3794180379418037953071128Lysinibacillus sphaericus C3-41, complete genometryptophan synthase subunit beta1e-0758.2
NC_013385:90331:9743797437986481212Ammonifex degensii KC4, complete genomethreonine synthase1e-0758.2
NC_012778:748143:760741760741761706966Eubacterium eligens ATCC 27750, complete genomecysteine synthase2e-0757.8
NC_019962:3577846:3598543359854335998201278Natrinema pellirubrum DSM 15624, complete genomethreonine synthase3e-0757
NC_013849:627811:6422306422306433961167Ferroglobus placidus DSM 10642 chromosome, complete genomethreonine synthase3e-0757
NC_013156:21781:3887138871400881218Methanocaldococcus fervens AG86, complete genomethreonine synthase3e-0757
NC_009051:657000:6928926928926940971206Methanoculleus marisnigri JR1, complete genomethreonine synthase3e-0757
NC_015589:7678:1861418614198221209Desulfotomaculum ruminis DSM 2154 chromosome, complete genomePyridoxal-5'-phosphate-dependent protein subunit beta3e-0757
NC_009428:833701:8337018337018347351035Rhodobacter sphaeroides ATCC 17025 chromosome, complete genomecysteine synthase A3e-0757
NC_019974:3013338:3022611302261130238641254Natronococcus occultus SP4, complete genomethreonine dehydratase, medium form3e-0757
NC_008529:1265958:127125812712581272181924Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365, completeCysteine synthase4e-0756.6
NC_008942:1446682:1449456144945614506551200Methanocorpusculum labreanum Z, complete genomeNAD-dependent epimerase/dehydratase5e-0756.2
NC_021182:4088000:409033140903314091239909Clostridium pasteurianum BC1, complete genomecysteine synthase6e-0756.2
NC_008698:560529:5639355639355651611227Thermofilum pendens Hrk 5, complete genomethreonine dehydratase6e-0755.8
NC_009465:938378:9770439770439782481206Candidatus Vesicomyosocius okutanii HA, complete genometryptophan synthase subunit beta2e-0654.7
NC_014961:1235500:1237046123704612381071062Desulfurococcus mucosus DSM 2162 chromosome, complete genomeL-threonine synthase3e-0653.5
NC_015216:584841:5929855929855941841200Methanobacterium sp. AL-21 chromosome, complete genomethreonine synthase3e-0653.5
NC_014479:3079855:3102537310253731035951059Bacillus subtilis subsp. spizizenii str. W23 chromosome, completethreonine synthase3e-0653.5
NC_007604:2213659:2226908222690822281701263Synechococcus elongatus PCC 7942, complete genometryptophan synthase, beta subunit5e-0653.1
NC_006576:2073163:2088860208886020901221263Synechococcus elongatus PCC 6301, complete genometryptophan synthase subunit beta5e-0653.1
NC_004193:375416:5544935544935556921200Oceanobacillus iheyensis HTE831, complete genometryptophan synthase subunit beta4e-0653.1
NC_015555:2359000:2372254237225423733121059Thermoanaerobacterium xylanolyticum LX-11 chromosome, completethreonine synthase4e-0653.1
NC_019673:7598026:7598026759802675992491224Saccharothrix espanaensis DSM 44229 complete genomeTryptophan synthase beta chain4e-0653.1
NC_014171:71963:737477374774670924Bacillus thuringiensis BMB171 chromosome, complete genomecysteine synthase6e-0652.8
NC_014410:2609588:2622708262270826237631056Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,threonine synthase6e-0652.8
NC_010001:4703500:4707224470722447084081185Clostridium phytofermentans ISDg, complete genometryptophan synthase, beta subunit5e-0652.8
NC_017208:64500:732917329174214924Bacillus thuringiensis serovar chinensis CT-43 chromosome, completecysteine synthase5e-0652.8
NC_008702:1153344:116058311605831161473891Azoarcus sp. BH72, complete genomecysteine synthase B5e-0652.8
NC_016148:1877711:1917067191706719182571191Thermovirga lienii DSM 17291 chromosome, complete genometryptophan synthase subunit beta7e-0652.4
NC_005042:165530:1860941860941873441251Prochlorococcus marinus subsp. marinus str. CCMP1375, completetryptophan synthase subunit beta7e-0652.4
NC_009480:739395:739395739395740333939Clavibacter michiganensis subsp. michiganensis NCPPB 382, completehypothetical protein8e-0652.4
NC_021150:201237:2059812059812072011221Azotobacter vinelandii CA6, complete genometryptophan synthase subunit beta9e-0652
NC_012560:201237:2059812059812072011221Azotobacter vinelandii DJ, complete genomeTryptophan synthase, beta chain; TrypB9e-0652