Pre_GI: BLASTP Hits

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Query: NC_016512:2388612:2388612 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Start: 2388612, End: 2390681, Length: 2070

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:2380131:2380131238013123822002070Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeNAD+ synthetase01353
NC_016511:2389273:2389273238927323913422070Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeNAD+ synthetase01353
NC_014039:2386347:2386347238634723884162070Propionibacterium acnes SK137 chromosome, complete genomeNAD+ synthetase01353
NC_013235:508585:5335415335415355802040Nakamurella multipartita DSM 44233, complete genomeNAD+ synthetase0787
NC_012032:1878854:1894441189444118965342094Chloroflexus sp. Y-400-fl, complete genomeNAD+ synthetase0679
NC_007484:2392739:2407810240781024099542145Nitrosococcus oceani ATCC 19707, complete genomeNAD(+) synthetase8e-173607
NC_014315:1042556:1047280104728010493732094Nitrosococcus watsoni C-113 chromosome, complete genomeNAD+ synthetase1e-172607
NC_016627:1452688:1468084146808414700061923Clostridium clariflavum DSM 19732 chromosome, complete genomeNAD+ synthetase1e-133477
NC_014624:3810163:3815494381549438174911998Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein1e-132474
NC_013203:202008:2124112124112144412031Atopobium parvulum DSM 20469, complete genomeNAD+ synthetase6e-131468
NC_015977:935798:9688139688139707231911Roseburia hominis A2-183 chromosome, complete genomeNAD synthetase1e-128460
NC_015389:809474:8479988479988500792082Coriobacterium glomerans PW2 chromosome, complete genomeNAD+ synthetase9e-115414
NC_020419:782337:7962637962637981551893Uncultured Termite group 1 bacterium phylotype Rs-D17 DNA, completeNAD+ synthetase2e-114414
NS_000191:782337:7962637962637981551893Uncultured Termite group 1 bacterium phylotype Rs-D17, completeNAD+ synthetase2e-114414
NC_004557:691944:6956406956406975591920Clostridium tetani E88, complete genomeNAD(+) synthetase5e-109395
NC_008740:979830:9956529956529973161665Marinobacter aquaeolei VT8, complete genomeNAD+ synthetase1e-42174
NC_010003:2056000:2061126206112620628531728Petrotoga mobilis SJ95, complete genomeNAD+ synthetase2e-35151
NC_010995:3821327:3824981382498138266631683Cellvibrio japonicus Ueda107, complete genomeglutamine-dependent NAD+ synthetase signal peptide protein1e-34149
NC_012814:1856632:1868917186891718702511335Bifidobacterium animalis subsp. lactis Bl-04, complete genomeNAD+ synthetase4e-30133
NC_012815:1862373:1868691186869118700251335Bifidobacterium animalis subsp. lactis DSM 10140, complete genomeNAD+ synthetase4e-30133
NC_019970:813917:8300118300118316481638Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeNAD+ synthetase7e-29129
NC_012559:1228280:1230245123024512324642220Laribacter hongkongensis HLHK9, complete genomeNadE1e-28128
NC_008786:1936626:1936626193662619382841659Verminephrobacter eiseniae EF01-2, complete genomeNAD+ synthetase3e-28127
NC_021177:2034722:2056756205675620585101755Streptomyces fulvissimus DSM 40593, complete genomeNH(3)-dependent NAD(+) synthetase6e-28126
NC_007645:6049340:6052104605210460537441641Hahella chejuensis KCTC 2396, complete genomeNAD synthase6e-28126
NC_007333:1129826:1151497115149711532301734Thermobifida fusca YX, complete genomeNAD+ synthase5e-28126
NC_010688:1192410:1259945125994512616031659Xanthomonas campestris pv. campestris, complete genomeputative bifunctional NAD(+) synthase (glutamine-hydrolyzing) / nitrilase6e-26119
NC_016025:65923:7006270062717051644Candidatus Chloracidobacterium thermophilum B chromosome chromosomeNH(3)-dependent NAD(+) synthetase1e-25118
NC_007643:791500:8110368110368127121677Rhodospirillum rubrum ATCC 11170, complete genomeNAD(+) synthase (glutamine-hydrolyzing)7e-25116
NC_010681:1234500:1258558125855812602581701Burkholderia phytofirmans PsJN chromosome 1, complete sequenceNAD+ synthetase1e-24115
NC_015953:1860946:1877515187751518792691755Streptomyces sp. SirexAA-E chromosome, complete genomeNAD+ synthetase2e-23111
NC_014844:3538432:3552157355215735538271671Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomeNAD+ synthetase1e-22108
NC_015732:2680182:2696083269608326978071725Spirochaeta caldaria DSM 7334 chromosome, complete genomeNAD+ synthetase9e-22105
NC_015416:1571451:1599884159988416015361653Methanosaeta concilii GP-6 chromosome, complete genomeglutamine-dependent NAD(+) synthetase4e-21103
NC_017243:1698000:1703463170346317053551893Brachyspira intermedia PWS/A chromosome, complete genomeD+ synthetase4e-20100
NC_015424:3890293:3895074389507438966961623Aeromonas veronii B565 chromosome, complete genomeglutamine-dependent NAD(+) synthetase5e-20100
NC_019908:700000:7179087179087197851878Brachyspira pilosicoli P43/6/78 chromosome, complete genomeNAD+ synthetase8e-2099.4
NC_012225:569590:5752875752875771791893Brachyspira hyodysenteriae WA1, complete genomeD+ synthetase1e-1998.6
NC_018604:1489567:1490305149030514921821878Brachyspira pilosicoli WesB complete genomeNAD+synthetase2e-1997.8
NC_014330:2520906:2520906252090625227831878Brachyspira pilosicoli 95/1000 chromosome, complete genomeNAD+synthetase1e-1895.5
NC_008319:2007752:2009683200968320114041722Synechococcus sp. CC9311, complete genomeNAD+ synthetase5e-1893.2
NC_012815:1862373:186812018681201868656537Bifidobacterium animalis subsp. lactis DSM 10140, complete genomeNAD synthetase1e-1792.4
NC_012814:1856632:186834618683461868882537Bifidobacterium animalis subsp. lactis Bl-04, complete genomeNAD synthetase1e-1792.4
NC_014507:1373325:1387227138722713888791653Methanoplanus petrolearius DSM 11571 chromosome, complete genomeNAD+ synthetase5e-1686.7
NC_015563:1129469:1132157113215711338571701Delftia sp. Cs1-4 chromosome, complete genomeNAD+ synthetase6e-1686.7
NC_014414:167803:1806111806111822781668Parvularcula bermudensis HTCC2503 chromosome, complete genomeNAD(+) synthase5e-1480.1
NC_009952:592000:5936705936705953431674Dinoroseobacter shibae DFL 12, complete genomeglutamine-dependent NAD(+) synthetase1e-1379
NC_015672:1921023:193498619349861935801816Flexistipes sinusarabici DSM 4947 chromosome, complete genomeNH(3)-dependent NAD(+) synthetase4e-1377.4
NC_000854:1222836:123770512377051238565861Aeropyrum pernix K1, complete genomeNH(3)-dependent NAD(+) synthetase6e-1376.6
NC_008260:497855:5147345147345163591626Alcanivorax borkumensis SK2, complete genomeNAD+ synthase (glutamine-hydrolysing)8e-1376.3
NC_015160:2521849:2522714252271425242821569Odoribacter splanchnicus DSM 20712 chromosome, complete genomeNAD+ synthetase3e-1274.3
NC_017954:1:9284928410129846Thermogladius cellulolyticus 1633 chromosome, complete genomeNAD+ synthetase1e-1172.4
NC_013385:1882549:1887139188713918887661628Ammonifex degensii KC4, complete genome3e-1170.9
NC_019974:298523:316282316282317076795Natronococcus occultus SP4, complete genomeNH(3)-dependent NAD(+) synthetase8e-1169.7
NC_009776:1249350:125212512521251252952828Ignicoccus hospitalis KIN4/I, complete genomeNH(3)-dependent NAD(+) synthetase1e-0862.4
NC_010644:718748:718748718748719563816Elusimicrobium minutum Pei191, complete genomeNAD+ synthetase9e-0859.3
NC_007426:1840670:184229918422991843126828Natronomonas pharaonis DSM 2160, complete genomeNAD(+) synthase (glutamine-hydrolyzing) 11e-0759.3
NC_014471:849032:877730877730878557828Ignisphaera aggregans DSM 17230 chromosome, complete genomeNH(3)-dependent NAD(+) synthetase2e-0758.2
NC_013385:1617338:162092316209231621654732Ammonifex degensii KC4, complete genomeNAD+ synthetase3e-0757.4
NC_013939:441921:449570449570450397828Deferribacter desulfuricans SSM1, complete genomeNAD(+) synthase1e-0655.8