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Query: NC_016511:1811171:1831931 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Start: 1831931, End: 1832581, Length: 651

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006085:1859191:187998918799891880642654Propionibacterium acnes KPA171202, complete genomeputative uridine kinase2e-111400
NC_014039:1813205:183413818341381834656519Propionibacterium acnes SK137 chromosome, complete genomehypothetical protein1e-95348
NC_013530:423540:441608441608442273666Xylanimonas cellulosilytica DSM 15894, complete genomeUridine kinase-like protein3e-29128
NC_012803:1117875:113810911381091138729621Micrococcus luteus NCTC 2665, complete genomeuridine kinase1e-22106
NC_016582:5769080:579043757904375791099663Streptomyces bingchenggensis BCW-1 chromosome, complete genomeuridine kinase4e-1684.7