Some Help

Query: NC_016511:1811171:1818841 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Start: 1818841, End: 1819311, Length: 471

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:1799521:180975118097511810221471Propionibacterium acnes TypeIA2 P.acn33 chromosome, completedicarboxylate carrier MatC domain protein7e-73272
NC_016512:1810625:181829518182951818765471Propionibacterium acnes TypeIA2 P.acn17 chromosome, completedicarboxylate carrier MatC domain protein7e-73272
NC_014039:1813205:182091118209111821381471Propionibacterium acnes SK137 chromosome, complete genomedicarboxylate carrier MatC domain protein4e-71266
NC_011740:3739395:374693037469303747805876Escherichia fergusonii ATCC 35469, complete genomehypothetical protein3e-25114