Pre_GI: BLASTP Hits

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Query: NC_016511:1354949:1373200 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Start: 1373200, End: 1374528, Length: 1329

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:1345840:1364090136409013654181329Propionibacterium acnes TypeIA2 P.acn33 chromosome, completesurfactin synthetase subunit 10884
NC_006085:1379370:1397602139760214008983297Propionibacterium acnes KPA171202, complete genomesurfactin synthetase subunit 10882
NC_016512:1357225:1372645137264513737541110Propionibacterium acnes TypeIA2 P.acn17 chromosome, completesurfactin synthetase subunit 10721
NC_016112:1735044:1729783172978317350475265Methylomicrobium alcaliphilum chromosome, complete genomenon-ribosomal peptide synthetase2e-1790.9
NC_020126:5558613:55887025588702560639217691Myxococcus stipitatus DSM 14675, complete genomeamino acid adenylation domain-containing protein4e-1686.3
NC_020126:3383902:33920463392046341467722632Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase4e-1686.3
NC_020126:5608880:56088805608880562450615627Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase5e-1685.9
NC_020126:4974877:49748774974877499294218066Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase7e-1685.5
NC_015711:6266432:62884386288438630204813611Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase2e-1584.3
NC_014228:1929665:19314471931447194943117985Xenorhabdus nematophila ATCC 19061, complete genomeNon-ribosomal peptide synthetase6e-1582.4
NC_020126:4517133:45171334517133454241325281Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase1e-1481.3
NC_004547:1683593:17047321704732172730322572Erwinia carotovora subsp. atroseptica SCRI1043, complete genomenon-ribosomal peptide synthetase3e-1480.1
NC_020126:4517133:45440174544017455758513569Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase3e-1479.7
NC_007005:2191500:22177712217771223078113011Pseudomonas syringae pv. syringae B728a, complete genomepeptide synthase4e-1479.7
NC_021150:2546000:2563801256380125724378637Azotobacter vinelandii CA6, complete genomeNon-ribosomal peptide synthase, PvdD-like protein4e-1479.7
NC_012560:2546000:2563789256378925724258637Azotobacter vinelandii DJ, complete genomeNon-ribosomal peptide synthase, PvdD-like protein4e-1479.7
NC_017093:5225864:52415715241571525403512465Actinoplanes missouriensis 431, complete genomeputative NRPS4e-1479.7
NC_015711:6266432:6285434628543462880042571Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase8e-1479
NC_002947:4805060:48182354818235483118812954Pseudomonas putida KT2440, complete genomepeptide synthase1e-1378.2
NC_016631:4087085:40870854087085410088113797Granulicella mallensis MP5ACTX8 chromosome, complete genomeamino acid adenylation protein2e-1377.4
NC_014228:1929665:19561861956186197262816443Xenorhabdus nematophila ATCC 19061, complete genomeputative Phenylalanine racemase (ATP-hydrolyzing)2e-1377.4
NC_015711:6796082:68133466813346682547712132Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase2e-1377
NC_004547:1683593:16835931683593170473921147Erwinia carotovora subsp. atroseptica SCRI1043, complete genomenon-ribosomal peptide synthetase2e-1377
NC_013440:3977097:4018547401854740245856039Haliangium ochraceum DSM 14365, complete genomeamino acid adenylation domain protein3e-1377
NC_014623:5942918:5962480596248059697907311Stigmatella aurantiaca DW4/3-1 chromosome, complete genomegrsb-like gramicidin s synthetase 23e-1377
NC_015711:6266432:62664326266432628385817427Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase6e-1375.9
NC_011655:230631:23869023869024881410125Bacillus cereus AH187 plasmid pAH187_270, complete sequencelinear gramicidin synthetase subunit D8e-1375.5
NC_015711:6796082:68254746825474683682211349Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthase/polyketide synthase7e-1375.5
NC_015711:6522808:65228086522808654153618729Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase/polyketide synthase9e-1375.1
NC_016792:13963:23886238863401610131Bacillus cereus NC7401 plasmid pNCcld, complete sequencecereulide biosynthesis protein9e-1375.1
NC_014623:5942918:5947265594726559569519687Stigmatella aurantiaca DW4/3-1 chromosome, complete genomegrsb-like gramicidin s synthetase 21e-1275.1
NC_014640:2754894:2767986276798627753447359Achromobacter xylosoxidans A8 chromosome, complete genomesyringomycin synthetase1e-1274.7
NC_013961:2579000:25830352583035260411221078Erwinia amylovora, complete genomeputative non-ribosomal peptide synthase2e-1274.3
NC_013971:2617000:26205632620563264164021078Erwinia amylovora ATCC 49946 chromosome, complete genomenon-ribosomal peptide synthetase2e-1274.3
NC_011655:230631:2306312306312386768046Bacillus cereus AH187 plasmid pAH187_270, complete sequencelinear gramicidin synthetase subunit B2e-1274.3
NC_016792:13963:1582715827238728046Bacillus cereus NC7401 plasmid pNCcld, complete sequencecereulide biosynthesis protein2e-1274.3
NC_012214:1267589:12777741277774129886021087Erwinia pyrifoliae Ep1/96, complete genomeNon-ribosomal peptide synthetase, similar to N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase4e-1273.2
NC_014623:5029932:50337425033742505252718786Stigmatella aurantiaca DW4/3-1 chromosome, complete genomebacitracin synthetase 14e-1273.2
NC_020126:4974877:49635174963517497488011364Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase4e-1272.8
NC_013892:1890500:1922507192250719291396633Xenorhabdus bovienii SS-2004 chromosome, complete genomeNon-ribosomal peptide synthetase (fragment)6e-1272.4
NC_013892:2108175:2126226212622621361919966Xenorhabdus bovienii SS-2004 chromosome, complete genomepeptide synthetase XpsB7e-1272.4
NC_012491:3115518:31155183115518313077515258Brevibacillus brevis NBRC 100599, complete genomelinear pentadecapeptide gramicidin synthetase LgrD1e-1171.6
NC_008095:4858117:48890534889053490039511343Myxococcus xanthus DK 1622, complete genomenon-ribosomal peptide synthase/polyketide synthase1e-1171.6
NC_008095:4858117:48754704875470488905613587Myxococcus xanthus DK 1622, complete genomenon-ribosomal peptide synthetase2e-1170.9
NC_004463:2262467:2276848227684822867809933Bradyrhizobium japonicum USDA 110, complete genomeprobable peptide synthetase2e-1170.5
NC_017249:7993713:7993713799371380022928580Bradyrhizobium japonicum USDA 6, complete genomehypothetical protein3e-1170.1
NC_015690:4469775:44697754469775449426024486Paenibacillus mucilaginosus KNP414 chromosome, complete genomeTyrocidine synthetase 32e-1067.4
NC_011725:2365647:23721142372114238699614883Bacillus cereus B4264 chromosome, complete genomebacitracin synthetase 13e-1067
NC_011772:2305000:23180482318048233293014883Bacillus cereus G9842, complete genomebacitracin synthetase 13e-1067
NC_014171:2350679:23571462357146237202814883Bacillus thuringiensis BMB171 chromosome, complete genomepeptide synthetase3e-1067
NC_003272:3148687:3160040316004031635343495Nostoc sp. PCC 7120, complete genomemultifunctional peptide synthetase2e-1067
NC_013892:1890500:18981991898199192251024312Xenorhabdus bovienii SS-2004 chromosome, complete genomephenylalanine racemase3e-1066.6
NC_008095:4189082:42203944220394423409713704Myxococcus xanthus DK 1622, complete genomenon-ribosomal peptide synthetase4e-1066.6
NC_016887:5295120:52951205295120533880843689Nocardia cyriacigeorgica GUH-2, complete genomenon-ribosomal peptide synthetase8e-1065.5
NC_016935:4233223:42332234233223424899015768Paenibacillus mucilaginosus 3016 chromosome, complete genometyrocidine synthetase 38e-1065.5
NC_016631:4087085:4101074410107441061945121Granulicella mallensis MP5ACTX8 chromosome, complete genomeamino acid adenylation protein1e-0965.1
NC_016631:4113794:41137944113794412770113908Granulicella mallensis MP5ACTX8 chromosome, complete genomeamino acid adenylation protein1e-0965.1
NC_015711:6266432:6302595630259563077875193Myxococcus fulvus HW-1 chromosome, complete genomenon-ribosomal peptide synthetase1e-0964.7
NC_013722:850307:85622285622287951323292Xanthomonas albilineans, complete genomeprobable non-ribosomal peptide synthetase protein2e-0963.9
NC_020126:6344827:6363701636370163689205220Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase3e-0963.2
NC_012962:3933715:3946923394692339542397317Photorhabdus asymbiotica, complete genomeGramicidin S synthetase 24e-0963.2
NC_012522:2031786:20357042035704204715411451Rhodococcus opacus B4, complete genomeputative non-ribosomal peptide synthetase4e-0963.2
NC_013722:1816561:18165611816561183919222632Xanthomonas albilineans, complete genomeprobable non-ribosomal peptide synthetase protein4e-0962.8
NC_013722:1785692:18165611816561183919222632Xanthomonas albilineans, complete genomeprobable non-ribosomal peptide synthetase protein4e-0962.8
NC_010995:2123909:21450372145037215688011844Cellvibrio japonicus Ueda107, complete genomeamino acid adenylation domain protein5e-0962.8
NC_014228:1929665:1949443194944319561716729Xenorhabdus nematophila ATCC 19061, complete genomeNon-ribosomal peptide synthetase (fragment)8e-0962
NC_017208:2432027:24384942438494245337314880Bacillus thuringiensis serovar chinensis CT-43 chromosome, completepeptide synthetase9e-0962
NC_014483:4532000:45360094536009455494718939Paenibacillus polymyxa E681 chromosome, complete genomeBacitracin synthetase 31e-0861.6
NC_012962:3933715:39359643935964394691910956Photorhabdus asymbiotica, complete genomeGramicidin S synthetase 21e-0861.2
NC_011898:2713912:2730399273039927401069708Clostridium cellulolyticum H10, complete genomeamino acid adenylation domain protein2e-0861.2
NC_014639:1538782:15387821538782155072411943Bacillus atrophaeus 1942 chromosome, complete genomeMycosubtilin synthase subunit A2e-0860.8
CP002207:1538782:15387821538782155072411943Bacillus atrophaeus 1942, complete genomeMycosubtilin synthase subunit A2e-0860.8
NC_016584:3826300:3829172382917238363207149Desulfosporosinus orientis DSM 765 chromosome, complete genomeamino acid adenylation enzyme/thioester reductase family protein2e-0860.5
NC_007005:4411388:44113884411388443141820031Pseudomonas syringae pv. syringae B728a, complete genomeAmino acid adenylation3e-0860.5
NC_016906:1268606:12931731293173130936616194Gordonia polyisoprenivorans VH2 chromosome, complete genomeputative non-ribosomal peptide synthetase3e-0860.1
NC_018645:4277393:4299869429986943070687200Desulfobacula toluolica Tol2, complete genomeamino acid adenylation protein3e-0860.1
NC_011770:3163480:31634803163480317658313104Pseudomonas aeruginosa LESB58, complete genomePvdD(3)4e-0859.7
NC_014623:8463363:8476732847673284866889957Stigmatella aurantiaca DW4/3-1 chromosome, complete genomeLgrB-like linear gramicidin synthetase subunit B protein4e-0859.7
NC_007777:2841000:2880335288033528881527818Frankia sp. CcI3, complete genomeAmino acid adenylation6e-0859.3
NC_016582:7737930:7776051777605177795423492Streptomyces bingchenggensis BCW-1 chromosome, complete genomenon-ribosomal peptide synthetase6e-0859.3
NC_014640:2754894:2754894275489427601555262Achromobacter xylosoxidans A8 chromosome, complete genomeamino acid adenylation domain-containing protein 26e-0859.3
NC_014659:4299552:42995524299552431826518714Rhodococcus equi 103S, complete genomenon-ribosomal peptide synthetase6e-0859.3
NC_010162:9502480:95024809502480951351611037Sorangium cellulosum 'So ce 56', complete genomeNRPS/PKS hybrid9e-0858.5
NC_020410:1684192:17047571704757171942914673Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeNRPS/PKS protein baeJ1e-0758.5
NC_020156:144707:14936314936316417014808Nonlabens dokdonensis DSW-6, complete genomepeptide synthetase1e-0758.2
NC_013892:1890500:19291361929136195807928944Xenorhabdus bovienii SS-2004 chromosome, complete genomeOrnithine racemase1e-0758.2
NC_014483:4532000:45621874562187457704814862Paenibacillus polymyxa E681 chromosome, complete genomeGramicidin S synthetase II1e-0758.2
NC_013892:753307:77114577114578520514061Xenorhabdus bovienii SS-2004 chromosome, complete genomeOrnithine racemase1e-0757.8
NC_013722:1785692:17995971799597181656416968Xanthomonas albilineans, complete genomeprobable non-ribosomal peptide synthetase protein1e-0757.8
NC_013722:1816561:17995971799597181656416968Xanthomonas albilineans, complete genomeprobable non-ribosomal peptide synthetase protein1e-0757.8
NC_010125:2884762:29123572912357292571813362Gluconacetobacter diazotrophicus PAl 5, complete genomeputative nonribosomal peptide synthetases (NPRS)2e-0757.8
NC_017904:3415700:3408045340804534157037659Mycobacterium sp. MOTT36Y chromosome, complete genomelinear gramicidin synthetase subunit B2e-0757.4
NC_012997:2560324:25783042578304259351015207Teredinibacter turnerae T7901, complete genomenon-ribosomal peptide synthetase2e-0757.4
NC_015957:6119346:6191263619126361959004638Streptomyces violaceusniger Tu 4113 chromosome, complete genomeamino acid adenylation domain-containing protein3e-0757
NC_013892:2108175:21154932115493212622910737Xenorhabdus bovienii SS-2004 chromosome, complete genomepeptide synthetase XpsB3e-0757
NC_019673:4974422:4974422497442249807186297Saccharothrix espanaensis DSM 44229 complete genomeNon-ribosomal peptide synthetase3e-0757
NC_014172:166485:18497218497219542610455Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequencenonribosomal peptide synthetase C3e-0757
NC_020291:463500:4635004635004673303831Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomemycosubtilin synthase subunit A3e-0757
NC_016948:3381848:3374193337419333818517659Mycobacterium intracellulare MOTT-64 chromosome, complete genomelinear gramicidin synthetase subunit B4e-0756.6
NC_009727:1542000:1550118155011815563276210Coxiella burnetii Dugway 7E9-12, complete genome4e-0756.6
NC_016947:3309898:3302243330224333099017659Mycobacterium intracellulare MOTT-02 chromosome, complete genomelinear gramicidin synthetase subunit B4e-0756.6
NC_010546:3071377:3086580308658030897503171Cyanothece sp. ATCC 51142 chromosome circular, complete sequencepeptide synthetase5e-0756.2
NC_011726:1911500:1916360191636019240757716Cyanothece sp. PCC 8801, complete genomeamino acid adenylation domain protein5e-0756.2
NC_013161:1878700:1886187188618718939027716Cyanothece sp. PCC 8802, complete genomeamino acid adenylation domain protein4e-0756.2
NC_012721:1635999:1659257165925716660726816Burkholderia glumae BGR1 chromosome 2, complete genomeProbable peptide synthetase protein6e-0755.8
NC_011898:2713912:2719120271912027273788259Clostridium cellulolyticum H10, complete genomeamino acid adenylation domain protein7e-0755.8
NC_014483:2334500:23267152326715236886142147Paenibacillus polymyxa E681 chromosome, complete genomeBacitracin synthetase 17e-0755.8
NC_020126:3383902:3414674341467434213876714Myxococcus stipitatus DSM 14675, complete genomenon-ribosomal peptide synthetase7e-0755.8
NC_009142:2822260:2841069284106928442153147Saccharopolyspora erythraea NRRL 2338, complete genomenon-ribosomal peptide synthetase9e-0755.5
NC_004350:1252500:1259790125979012641574368Streptococcus mutans UA159, complete genomeputative bacitracin synthetase9e-0755.5
NC_013595:7195764:7195764719576471996813918Streptosporangium roseum DSM 43021, complete genomesiderophore 2,3-dihydroxybenzoate (DHB) synthesis protein8e-0755.5
NC_017093:5225864:5254032525403252592425211Actinoplanes missouriensis 431, complete genomeputative NRPS8e-0755.5
NC_011898:2796959:28090552809055282014211088Clostridium cellulolyticum H10, complete genomeamino acid adenylation domain protein7e-0755.5
NC_014722:1971305:19819841981984199935917376Burkholderia rhizoxinica HKI 454, complete genomeNon-ribosomal peptide synthetase modules7e-0755.5
NC_016791:2983349:2983349298334929917398391Clostridium sp. BNL1100 chromosome, complete genomeamino acid adenylation enzyme/thioester reductase family protein1e-0655.1
NC_016604:297687:29768729768730794610260Mycobacterium rhodesiae NBB3 chromosome, complete genomenon-ribosomal peptide synthase/amino acid adenylation enzyme1e-0655.1
NC_014718:232832:2445452445452520927548Burkholderia rhizoxinica HKI 454 chromosome, complete genomeNon-ribosomal peptide synthetase modules1e-0655.1
NC_014718:630188:64604264604265954413503Burkholderia rhizoxinica HKI 454 chromosome, complete genomeNon-ribosomal peptide synthetase modules1e-0655.1
NC_010612:90890:10308110308111475011670Mycobacterium marinum M, complete genomenon-ribosomal peptide synthetase1e-0655.1
NC_010612:103081:10308110308111475011670Mycobacterium marinum M, complete genomenon-ribosomal peptide synthetase1e-0655.1
NC_014623:5029932:50571475057147506818311037Stigmatella aurantiaca DW4/3-1 chromosome, complete genomen-(5-amino-5-carboxypentanoyl)-l-cysteinyl-d- valine synthase1e-0654.7
NC_012962:3499900:35110903511090353149220403Photorhabdus asymbiotica, complete genomeSimilar to proteins involved in antibiotic biosynthesis1e-0654.7
NC_012962:3060063:3080267308026730834643198Photorhabdus asymbiotica, complete genomesimilar to antibiotic synthetase1e-0654.7
NC_014622:2733000:27333692733369277562042252Paenibacillus polymyxa SC2 chromosome, complete genomebacillorin synthetase b2e-0654.3
NC_014718:102852:1143111143111226328322Burkholderia rhizoxinica HKI 454 chromosome, complete genomeNon-ribosomal peptide synthetase modules2e-0654.3
NC_006371:1973500:1986488198648819929946507Photobacterium profundum SS9 chromosome 2, complete sequencehypothetical peptide synthetase3e-0653.9
NC_008596:421882:4581884581884658677680Mycobacterium smegmatis str. MC2 155, complete genomelinear gramicidin synthetase subunit D3e-0653.9
NC_013960:1808523:1827233182723318326145382Nitrosococcus halophilus Nc4 chromosome, complete genomeamino acid adenylation domain protein2e-0653.9
NC_013093:5419458:54419135441913545295811046Actinosynnema mirum DSM 43827, complete genomeamino acid adenylation domain protein3e-0653.5
NC_014622:4922977:49317904931790494590414115Paenibacillus polymyxa SC2 chromosome, complete genomegramicidin s synthetase ii5e-0652.8
NC_008268:2313583:23169792316979232851911541Rhodococcus sp. RHA1, complete genomenon-ribosomal peptide synthetase5e-0652.8
NC_016604:297687:2900502900502976907641Mycobacterium rhodesiae NBB3 chromosome, complete genomeamino acid adenylation enzyme/thioester reductase family protein,thioester reductase-like protein5e-0652.8
NC_018750:8210500:8211951821195182162644314Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein6e-0652.4
NC_012490:2006716:20067162006716202041013695Rhodococcus erythropolis PR4, complete genomenon-ribosomal peptide synthetase8e-0652
NC_010397:4150596:4142854414285441505997746Mycobacterium abscessus chromosome Chromosome, complete sequenceProbable peptide synthetase NRP9e-0652