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Query: NC_016511:1354949:1364545 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Start: 1364545, End: 1365129, Length: 585

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:1345840:135543513554351356019585Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeplasmid partition protein ParA6e-98356
NC_006085:1379370:138896613889661389631666Propionibacterium acnes KPA171202, complete genomeplasmid partition protein ParA1e-97355
NC_016512:1357225:136399013639901364574585Propionibacterium acnes TypeIA2 P.acn17 chromosome, completeplasmid partition protein ParA7e-96349
NC_014550:3377834:340415434041543404747594Arthrobacter arilaitensis Re117, complete genomeParA family protein6e-1994
NC_017219:580093:599724599724600320597Bifidobacterium longum subsp. infantis ATCC 15697, complete genomehypothetical protein2e-1168.6
NC_011593:580318:599931599931600527597Bifidobacterium longum subsp. infantis ATCC 15697 chromosome,hypothetical protein2e-1168.6
NC_012808:1979000:198942619894261990091666Methylobacterium extorquens AM1, complete genomeputative ParA-like protein (chromosome partitioning)5e-0960.8
NC_015844:3159046:316873531687353169319585Zobellia galactanivorans, complete genomeconjugative transposon protein TraA2e-0755.5
NC_016800:694750:711896711896712135240Corynebacterium diphtheriae BH8 chromosome, complete genomechromosome partitioning protein8e-0753.5
NC_016788:655175:674063674063674302240Corynebacterium diphtheriae HC04 chromosome, complete genomehypothetical protein8e-0753.5
NC_009720:622262:653829653829654482654Xanthobacter autotrophicus Py2, complete genomecobyrinic acid ac-diamide synthase2e-0652
NC_010511:3674178:372664037266403727275636Methylobacterium sp. 4-46 chromosome, complete genomecobyrinic acid ac-diamide synthase3e-0652
NC_010170:4800000:482228048222804823236957Bordetella petrii, complete genomeputative partition protein3e-0651.6
NC_007650:2901751:290851329085132909175663Burkholderia thailandensis E264 chromosome II, complete sequenceParA family protein4e-0651.2
NC_008344:811386:830575830575831204630Nitrosomonas eutropha C91, complete genomeCobyrinic acid a,c-diamide synthase8e-0650.1