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Query: NC_016511:1212282:1218966 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Start: 1218966, End: 1219901, Length: 936

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014039:1238500:124528012452801246248969Propionibacterium acnes SK137 chromosome, complete genomeBadF/BadG/BcrA/BcrD ATPase family protein2e-159561
NC_016512:1211653:121832812183281219272945Propionibacterium acnes TypeIA2 P.acn17 chromosome, completeBadF/BadG/BcrA/BcrD ATPase family protein4e-159560
NC_016516:1203000:120978312097831210718936Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeBadF/BadG/BcrA/BcrD ATPase family protein5e-159560
NC_006085:1234587:124327412432741244209936Propionibacterium acnes KPA171202, complete genomeputative N-acetylglucosamine kinase4e-139494
NC_012804:348235:363619363619364551933Thermococcus gammatolerans EJ3, complete genomeATPase, BadF/BadG/BcrA/BcrD type7e-0961.6
NC_015677:3179910:319436731943673195287921Ramlibacter tataouinensis TTB310 chromosome, complete genomeN-acetylglucosamine kinase8e-0754.7
NC_006177:324363:327052327052327987936Symbiobacterium thermophilum IAM 14863, complete genomehypothetical protein3e-0652.8