Pre_GI: BLASTP Hits

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Query: NC_016511:1212282:1216075 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Start: 1216075, End: 1216989, Length: 915

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:1203000:120689212068921207806915Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeN-acetylmuramic acid 6-phosphate etherase5e-156550
NC_016512:1211653:121544612154461216360915Propionibacterium acnes TypeIA2 P.acn17 chromosome, completeN-acetylmuramic acid 6-phosphate etherase5e-156550
NC_014039:1238500:124242212424221243336915Propionibacterium acnes SK137 chromosome, complete genomeN-acetylmuramic acid 6-phosphate etherase1e-155549
NC_006085:1234587:124038312403831241297915Propionibacterium acnes KPA171202, complete genomehypothetical protein2e-153541
NC_014837:387868:391840391840392751912Pantoea sp. At-9b chromosome, complete genomeglucokinase regulatory-like protein2e-76286
NC_008800:4013298:402724340272434028151909Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,N-acetylmuramic acid 6-phosphate etherase1e-74279
NC_014219:192555:200665200665201573909Bacillus selenitireducens MLS10 chromosome, complete genomeglucokinase regulatory-like protein2e-73275
NC_015224:3892972:390449839044983905406909Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,N-acetylmuramic acid-6-phosphate etherase3e-73275
NC_012880:3241886:324310632431063243999894Dickeya dadantii Ech703, complete genomeglucokinase regulatory-like protein6e-72270
NC_003909:927955:936780936780937664885Bacillus cereus ATCC 10987, complete genomehypothetical protein9e-71266
NC_012913:1867276:188233018823301883244915Aggregatibacter aphrophilus NJ8700, complete genomeN-acetylmuramic acid 6-phosphate etherase6e-70264
NC_020272:3706722:373035337303533731282930Bacillus amyloliquefaciens IT-45, complete genomeN-acetylmuramic acid-6-phosphate etherase1e-69263
NC_014410:2329838:234186623418662342771906Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,glucokinase regulatory-like protein protein1e-68259
NC_012912:1229333:124358912435891244530942Dickeya zeae Ech1591, complete genomeglucokinase regulatory-like protein3e-68258
NC_013171:1677543:167668716766871677562876Anaerococcus prevotii DSM 20548, complete genomeglucokinase regulatory-like protein2e-67255
NC_016937:1525914:154661915466191547503885Francisella tularensis subsp. tularensis TI0902 chromosome,N-acetylmuramic acid 6-phosphate etherase4e-67254
NC_008245:1525877:154658215465821547466885Francisella tularensis subsp. tularensis FSC 198, complete genomeglucokinase regulatory protein4e-67254
NC_009257:775538:775538775538776422885Francisella tularensis subsp. tularensis WY96-3418 chromosome,N-acetylmuramic acid 6-phosphate etherase5e-67254
NC_014377:321949:342080342080343006927Thermosediminibacter oceani DSM 16646 chromosome, complete genomeglucokinase regulatory-like protein1e-66253
NC_008601:1560482:159865815986581599542885Francisella tularensis subsp. novicida U112, complete genomeglucokinase regulatory protein1e-66253
NC_004193:375416:642516642516643400885Oceanobacillus iheyensis HTE831, complete genomehypothetical protein5e-66251
NC_014334:99000:116710116710117639930Lactobacillus casei str. Zhang chromosome, complete genomeputative sugar phosphate isomerase7e-66250
NC_008526:74500:115575115575116504930Lactobacillus casei ATCC 334, complete genomePredicted sugar phosphate isomerase2e-65249
NC_014106:1658103:165920016592001660099900Lactobacillus crispatus ST1, complete genomeN-acetylmuramic acid 6-phosphate etherase4e-63241
NC_010163:285710:294455294455295369915Acholeplasma laidlawii PG-8A chromosome, complete genomeglutamine---fructose-6-phosphate transaminase2e-62239
NC_010674:3141228:316231431623143163219906Clostridium botulinum B str. Eklund 17B, complete genomeN-acetylmuramic acid 6-phosphate etherase6e-61234
NC_007509:832473:834331834331835236906Burkholderia sp. 383 chromosome 3, complete sequencehypothetical protein9e-57220
NC_009481:1109324:113985011398501140800951Synechococcus sp. WH 7803 chromosome, complete genomeN-acetylmuramic acid 6-phosphate etherase5e-54211
NC_015638:23654:295462954630358813Lacinutrix sp. 5H-3-7-4 chromosome, complete genomeN-acetylmuramic acid 6-phosphate etherase4e-54211
NC_015496:2436089:244889324488932449840948Krokinobacter diaphorus 4H-3-7-5 chromosome, complete genomeglucokinase regulatory-like protein9e-52204
NC_016610:61661:616616166162494834Tannerella forsythia ATCC 43037 chromosome, complete genomeN-acetylmuramic acid 6-phosphate etherase9e-47187
NC_014933:510164:532954532954533775822Bacteroides helcogenes P 36-108 chromosome, complete genomesugar isomerase (SIS)1e-46186
NC_014934:3218423:322224432222443223059816Cellulophaga algicola DSM 14237 chromosome, complete genomen-acetylmuramic acid 6-phosphate etherase7e-46184
NC_014618:1809369:181561918156191816551933Enterobacter cloacae SCF1 chromosome, complete genomehypothetical protein3e-40166
NC_018145:50237:646306463065538909Zymomonas mobilis subsp. mobilis ATCC 29191 chromosome, completesugar isomerase (SIS)3e-36152
NC_006526:1303635:130591313059131306866954Zymomonas mobilis subsp. mobilis ZM4, complete genomehypothetical protein2e-35150