Pre_GI: BLASTN Hits

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Query: NC_015848:1105892 Mycobacterium canettii CIPT 140010059, complete genome

Start: 1105892, End: 1127326, Length: 21435

Host Lineage: Mycobacterium canettii; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: The Republic of Djibouti, Africa appears to be an exceptional place in terms of tuberculosis (TB) caused by Mycobacterium canettii, a highly unusual tubercle bacillus with unusual smooth colony morphology (STB) related to the M. tuberculosis complex (MTBC). M. canettii was first isolated from a 20-year-old French farmer suffering from pulmonary tuberculosis by G. Canetti in 1969. Since then, this strain has been isolated on rare occasions from patients who lived or were presumably infected in East Africa. It tends to preferentially affect children and foreigners in the Horn of Africa. M. canettii, a possible ancestor of the MTBC, is found almost exclusively in the Horn of Africa where TB is thought to have emerged about 40 000 years ago, coinciding with the expansion of human population out of Africa. The geographical restriction of M. canettii isolates and contrasting genetic diversity are characteristics compatible with a non-human reservoir. With the larger pan-genome reflecting the ancestral, wider gene pool of tubercle bacilli, their lower virulence and faster growth, especially at temperatures below 37 degrees C, plausibly reflecting broader environmental adaptability, STB strains might thus come nearer to the as-yet-unknown missing link between the obligate pathogen M. tuberculosis and environmental mycobacteria (adapted from PMIDs 20831613 and 23291586). Mycobacteria have an unusual outer membrane approximately 8nm thick, despite being considered Gram-positive. The outer membrane and the mycolic acid-arabinoglactan-peptidoglycan polymer form the cell wall, which constitutes an efficient permeability barrier in conjunction with the cell inner membrane.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_015138:11430151143015116543022416Acidovorax avenae subsp. avenae ATCC 19860 chromosome, complete2e-1075.8BLASTN svgBLASTP svg
NC_011992:77390577390579750923605Acidovorax ebreus TPSY, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014318:7821227*7821227785959938373Amycolatopsis mediterranei U32 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_008618:10915*109153564524731Bifidobacterium adolescentis ATCC 15703, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010407:32960*329605163318674Clavibacter michiganensis subsp. sepedonicus chromosome, complete2e-19105BLASTN svgBLASTP svg
NC_020302:22193782219378224609926722Corynebacterium halotolerans YIM 70093 = DSM 44683, complete7e-1073.8BLASTN svgBLASTP svg
NC_010545:1729161*1729161175559626436Corynebacterium urealyticum DSM 7109, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_002936:1395432*1395432141906223631Dehalococcoides ethenogenes 195, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_014958:843456*84345686943725982Deinococcus maricopensis DSM 21211 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_008278:81866*8186610216620301Frankia alni ACN14a, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_007777:75885758859809922215Frankia sp. CcI3, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_013441:14870581487058151769130634Gordonia bronchialis DSM 43247, complete genome9e-31143BLASTN svgBLASTP svg
NC_014323:4619344*4619344465241733074Herbaspirillum seropedicae SmR1 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_013174:23421*234216198738567Jonesia denitrificans DSM 20603, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_012803:1094679*1094679111581321135Micrococcus luteus NCTC 2665, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_015635:3860570*3860570389185531286Microlunatus phosphovorus NM-1, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_010397:1099312*1099312112264723336Mycobacterium abscessus chromosome Chromosome, complete sequence4e-39170BLASTN svgBLASTP svg
NC_002945:1095337*1095337111759922263Mycobacterium bovis AF2122/97, complete genome039300BLASTN svgBLASTP svg
NC_008769:1125567*1125567114763722071Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome039290BLASTN svgBLASTP svg
NC_012207:1097228*1097228111789920672Mycobacterium bovis BCG str. Tokyo 172, complete genome037780BLASTN svgBLASTP svg
NC_020133:50205005020500504274122242Mycobacterium liflandii 128FXT, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_010612:54030005403000542141218413Mycobacterium marinum M, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_014814:3926676*3926676394894522270Mycobacterium sp. Spyr1 chromosome, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_002755:1095105*1095105111578720683Mycobacterium tuberculosis CDC1551, complete genome037750BLASTN svgBLASTP svg
NC_009565:1098847*1098847112029321447Mycobacterium tuberculosis F11, complete genome039230BLASTN svgBLASTP svg
NC_009525:1096386*1096386111845622071Mycobacterium tuberculosis H37Ra, complete genome039250BLASTN svgBLASTP svg
NC_000962:1095078*1095078111574920672Mycobacterium tuberculosis H37Rv, complete genome037740BLASTN svgBLASTP svg
NC_006361:5146000*5146000517359927600Nocardia farcinica IFM 10152, complete genome2e-38168BLASTN svgBLASTP svg
NC_008699:833737*83373785664022904Nocardioides sp. JS614, complete genome2e-19105BLASTN svgBLASTP svg
NC_018524:444217*44421747409929883Nocardiopsis alba ATCC BAA-2165 chromosome, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_021064:1789980*1789980181232622347Propionibacterium avidum 44067, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_014215:1929000*1929000194714618147Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,7e-19103BLASTN svgBLASTP svg
NC_015312:848403*84840386771719315Pseudonocardia dioxanivorans CB1190 chromosome, complete genome3e-18101BLASTN svgBLASTP svg
NC_015677:3339181*3339181336388124701Ramlibacter tataouinensis TTB310 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_008268:5781604*5781604581424432641Rhodococcus sp. RHA1, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_008148:30248673024867304671521849Rubrobacter xylanophilus DSM 9941, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_013159:3554389*3554389357362219234Saccharomonospora viridis DSM 43017, complete genome9e-31143BLASTN svgBLASTP svg
NC_014168:471000*47100049425123252Segniliparus rotundus DSM 44985 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_006177:835459*83545985883523377Symbiobacterium thermophilum IAM 14863, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_006177:280234*28023431920738974Symbiobacterium thermophilum IAM 14863, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_013510:1786194*1786194181369827505Thermomonospora curvata DSM 43183, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_005835:1345790*1345790136952723738Thermus thermophilus HB27, complete genome2e-0765.9BLASTN svgBLASTP svg