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Query: NC_015571:801715:806479 Porphyromonas gingivalis TDC60, complete genome

Start: 806479, End: 808527, Length: 2049

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015311:1860666:1902436190243619045022067Prevotella denticola F0289 chromosome, complete genomeToprim domain-containing protein0820
NC_015311:2531616:2543048254304825451082061Prevotella denticola F0289 chromosome, complete genomeToprim domain-containing protein0801
NC_016776:5174606:5221669522166952237952127Bacteroides fragilis 638R, complete genomehypothetical protein0696
NC_003228:2010643:2021655202165520237542100Bacteroides fragilis NCTC 9343, complete genomehypothetical protein0680
NC_014933:220146:2347602347602368592100Bacteroides helcogenes P 36-108 chromosome, complete genomehypothetical protein0680
NC_002950:879930:9116569116569128221167Porphyromonas gingivalis W83, complete genomehypothetical protein3e-152539
NC_010729:619664:6408696408696421971329Porphyromonas gingivalis ATCC 33277, complete genomehypothetical protein1e-127457
NC_015164:2859000:2887838288783828889111074Bacteroides salanitronis DSM 18170 chromosome, complete genomehypothetical protein2e-1998.6
NC_015164:493159:5375125375125386091098Bacteroides salanitronis DSM 18170 chromosome, complete genomehypothetical protein1e-1895.5
NC_006347:3199511:3203615320361532047211107Bacteroides fragilis YCH46, complete genomehypothetical protein4e-1790.5
NC_013730:834500:8521808521808532981119Spirosoma linguale DSM 74, complete genomehypothetical protein7e-1789.7
NC_015160:2145915:2166118216611821671911074Odoribacter splanchnicus DSM 20712 chromosome, complete genomehypothetical protein3e-1584
NC_002950:879930:9039009039009049641065Porphyromonas gingivalis W83, complete genomemobilizable transposon, hypothetical protein, putative9e-1582.8
NC_019968:1304450:1330052133005213311041053Prevotella dentalis DSM 3688 chromosome 2, complete sequencehypothetical protein1e-1379
NC_015571:2002489:2021699202169920227631065Porphyromonas gingivalis TDC60, complete genomemobilizable transposon protein1e-1275.9
NC_007356:1165760:1170232117023211724392208Dehalococcoides sp. CBDB1, complete genomehypothetical protein6e-0756.6
NC_014033:103020:1305181305181316451128Prevotella ruminicola 23 chromosome, complete genomehypothetical protein4e-0653.9