Pre_GI: BLASTP Hits

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Query: NC_015571:290355:308005 Porphyromonas gingivalis TDC60, complete genome

Start: 308005, End: 308670, Length: 666

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002950:2098454:211169821116982112363666Porphyromonas gingivalis W83, complete genomeCRISPR-associated TM1814 family protein5e-128456
NC_013501:1881692:190572019057201906439720Rhodothermus marinus DSM 4252, complete genomeCRISPR-associated protein Cas64e-33141
NC_015966:1316901:131891313189131319635723Rhodothermus marinus SG0.5JP17-172 chromosome, complete genomeCRISPR-associated protein Cas62e-32139
NC_010803:483713:489413489413490213801Chlorobium limicola DSM 245, complete genomeCRISPR-associated protein Cas64e-0755.1