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Query: NC_015571:168617:184533 Porphyromonas gingivalis TDC60, complete genome

Start: 184533, End: 185162, Length: 630

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010729:2038118:2049047204904720504441398Porphyromonas gingivalis ATCC 33277, complete genomehypothetical protein6e-31134
NC_010729:2038118:2041638204163820478956258Porphyromonas gingivalis ATCC 33277, complete genomehypothetical protein2e-1892
NC_010729:2038118:2052907205290720540941188Porphyromonas gingivalis ATCC 33277, complete genomehypothetical protein5e-79293
NC_010729:2038118:205246520524652052776312Porphyromonas gingivalis ATCC 33277, complete genomehypothetical protein7e-28123
NC_015571:168617:1799901799901813901401Porphyromonas gingivalis TDC60, complete genomeputative integrin subunit alpha5e-29127
NC_015571:168617:1721271721271784506324Porphyromonas gingivalis TDC60, complete genomehypothetical protein3e-1891.7
NC_016610:1974527:1977357197735719792431887Tannerella forsythia ATCC 43037 chromosome, complete genomeRHS repeat-associated core domain-containing protein2e-21102