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Query: NC_015571:168617:179466 Porphyromonas gingivalis TDC60, complete genome

Start: 179466, End: 179942, Length: 477

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002950:1981155:198799619879961988505510Porphyromonas gingivalis W83, complete genomehypothetical protein1e-79294
NC_015571:168617:184011184011184487477Porphyromonas gingivalis TDC60, complete genomehypothetical protein4e-75279
NC_010729:2038118:204852620485262048987462Porphyromonas gingivalis ATCC 33277, complete genomehypothetical protein1e-57221
NC_015571:168617:178455178455178904450Porphyromonas gingivalis TDC60, complete genomehypothetical protein2e-1271.6
NC_016610:1974527:198141719814171981887471Tannerella forsythia ATCC 43037 chromosome, complete genomehypothetical protein2e-0961.6
NC_015571:168617:186500186500186910411Porphyromonas gingivalis TDC60, complete genomehypothetical protein8e-0649.3