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Query: NC_015425:718384 Clostridium botulinum BKT015925 chromosome, complete genome

Start: 718384, End: 741262, Length: 22879

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008593:640000*64000066264322644Clostridium novyi NT, complete genome7e-121442BLASTN svgBLASTP svg
NC_014328:40737144073714410040726694Clostridium ljungdahlii ATCC 49587 chromosome, complete genome1e-23119BLASTN svgBLASTP svg
NC_019970:2263427*2263427228281719391Thermoanaerobacterium thermosaccharolyticum M0795, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_020291:18105271810527182940518879Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-1385.7BLASTN svgBLASTP svg
NC_019978:2220863*2220863223957218710Halobacteroides halobius DSM 5150, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_015555:1989463*1989463201087221410Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete3e-0971.9BLASTN svgBLASTP svg
NC_003454:249304*24930426978820485Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete7e-0763.9BLASTN svgBLASTP svg
NC_015687:3302372*3302372332181219441Clostridium acetobutylicum DSM 1731 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_011025:183287*18328722741244126Mycoplasma arthritidis 158L3-1, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_008262:20256992025699204408118383Clostridium perfringens SM101, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_003030:3301342*3301342332018518844Clostridium acetobutylicum ATCC 824, complete genome3e-0661.9BLASTN svgBLASTP svg