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Query: NC_015425:641000 Clostridium botulinum BKT015925 chromosome, complete genome

Start: 641000, End: 664214, Length: 23215

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_008593:60972360972363291123189Clostridium novyi NT, complete genome2e-143517BLASTN svgBLASTP svg
NC_015662:110950*11095013012219173Buchnera aphidicola (Cinara tujafilina) chromosome, complete2e-19105BLASTN svgBLASTP svg
NC_014499:87528*8752810905021523Candidatus Sulcia muelleri CARI chromosome, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_008262:227354*22735427081243459Clostridium perfringens SM101, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_003366:25548025548029721641737Clostridium perfringens str. 13, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_020195:234392*23439225309918708Blattabacterium sp. (Blatta orientalis) str. Tarazona, complete1e-1179.8BLASTN svgBLASTP svg
NC_007633:446899*44689946595419056Mycoplasma capricolum subsp. capricolum ATCC 27343, complete1e-1179.8BLASTN svgBLASTP svg
NC_009850:2169459*2169459220320233744Arcobacter butzleri RM4018, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013454:229587*22958725413424548Blattabacterium sp. (Blattella germanica) str. Bge, complete2e-1075.8BLASTN svgBLASTP svg
NC_014751:449001*44900146805619056Mycoplasma leachii PG50 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_013123:78786*7878610552026735Candidatus Sulcia muelleri SMDSEM, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010674:3674739*3674739372221147473Clostridium botulinum B str. Eklund 17B, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_012780:18994918994920809218144Eubacterium eligens ATCC 27750 plasmid unnamed, complete sequence2e-0765.9BLASTN svgBLASTP svg
NC_005061:96536*9653614201245477Candidatus Blochmannia floridanus, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_014909:121771*12177114449822728Candidatus Blochmannia vafer str. BVAF chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_010723:3530000*3530000357960049601Clostridium botulinum E3 str. Alaska E43, complete genome7e-0763.9BLASTN svgBLASTP svg