Pre_GI: BLASTN Hits

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Query: NC_015425:369225 Clostridium botulinum BKT015925 chromosome, complete genome

Start: 369225, End: 392099, Length: 22875

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_021182:2360500*2360500238564325144Clostridium pasteurianum BC1, complete genome9e-31143BLASTN svgBLASTP svg
NC_020291:1*12890828908Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome1e-23119BLASTN svgBLASTP svg
NC_016012:16134*161347078354650Candidatus Arthromitus sp. SFB-rat-Yit, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013316:1081044*1081044111040629363Clostridium difficile R20291, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_009089:1202261*1202261123169329433Clostridium difficile 630, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_004557:691944*69194471563123688Clostridium tetani E88, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014614:26078226078228259921818Clostridium sticklandii, complete genome7e-0763.9BLASTN svgBLASTP svg