Pre_GI: BLASTP Hits

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Query: NC_015425:369225:388521 Clostridium botulinum BKT015925 chromosome, complete genome

Start: 388521, End: 389414, Length: 894

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011837:238160:264832264832265725894Clostridium kluyveri NBRC 12016, complete genomehypothetical protein6e-91334
NC_009706:238160:264832264832265725894Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein6e-91334
NC_014098:850000:850183850183851064882Bacillus tusciae DSM 2912 chromosome, complete genomehypothetical protein6e-47187
NC_015565:1920329:193435719343571935301945Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completehypothetical protein3e-33142
NC_011973:70764:938419384194737897Bacillus cereus Q1 plasmid pBc239, complete sequencehypothetical protein6e-32137
NC_017201:117485:133885133885134769885Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26,hypothetical protein7e-32137
NC_015573:1573621:159095215909521591845894Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomehypothetical protein3e-31135
NC_012473:46000:733707337074275906Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein1e-29130
NC_017203:73952:9955499554100489936Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281,hypothetical protein3e-27122
NC_011777:100631:102353102353103264912Bacillus cereus AH820 plasmid pAH820_272, complete sequencehypothetical protein3e-27122
NC_012579:72715:861088610887016909Bacillus anthracis str. CDC 684 plasmid pX01, complete sequencehypothetical protein5e-27121
NC_014331:57769:860678606787002936Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, completetranscriptional regulator6e-27121
NC_005707:12735:306383063831561924Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequencehypothetical protein2e-26119
NC_016792:143614:143614143614144537924Bacillus cereus NC7401 plasmid pNCcld, complete sequencehypothetical protein2e-26119
NC_011655:88336:883368833689259924Bacillus cereus AH187 plasmid pAH187_270, complete sequencehypothetical protein2e-26119
NC_012656:67949:860648606486960897Bacillus anthracis str. A0248 plasmid pXO1, complete sequencehypothetical protein9e-26117
NC_007322:57710:858008580086696897Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completehypothetical protein9e-26117
NC_007796:2966386:296983429698342970748915Methanospirillum hungatei JF-1, complete genomehypothetical protein1e-24114
NC_007796:2966386:297105529710552971930876Methanospirillum hungatei JF-1, complete genomehypothetical protein8e-25114
NC_007796:2966386:296865729686572969538882Methanospirillum hungatei JF-1, complete genomehypothetical protein6e-25114
NC_016641:1006662:102990710299071030527621Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein4e-24112
NC_015732:2680182:268018226801822681036855Spirochaeta caldaria DSM 7334 chromosome, complete genomehypothetical protein2e-2099.4
NC_018605:558391:575787575787576698912Cardinium endosymbiont cPer1 of Encarsia pergandiella, completehypothetical protein9e-2097.4
NC_018606:40000:540135401354948936Cardinium endosymbiont cPer1 of Encarsia pergandiella plasmidhypothetical protein5e-1995.1
NC_007940:1485006:150961115096111509994384Rickettsia bellii RML369-C, complete genomehypothetical protein1e-1894
NC_009883:1492425:151651915165191516926408Rickettsia bellii OSU 85-389, complete genomehypothetical protein1e-1893.6
NC_012225:787737:790676790676791551876Brachyspira hyodysenteriae WA1, complete genomehypothetical protein5e-1892
NC_014150:3053859:306122730612273062102876Brachyspira murdochii DSM 12563 chromosome, complete genomehypothetical protein7e-1891.3
NC_018605:846500:870873870873871820948Cardinium endosymbiont cPer1 of Encarsia pergandiella, completehypothetical protein1e-1790.5
NC_017243:1197586:121525812152581216109852Brachyspira intermedia PWS/A chromosome, complete genomehypothetical protein2e-1790.1
NC_011837:238160:265811265811266089279Clostridium kluyveri NBRC 12016, complete genomehypothetical protein7e-1788.2
NC_009706:238160:265814265814266089276Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-1686.7
NC_018607:1505908:152670415267041527558855Brachyspira pilosicoli B2904 chromosome, complete genomehypothetical protein6e-1685.1
NC_012225:880983:895847895847896713867Brachyspira hyodysenteriae WA1, complete genomehypothetical protein2e-1583.6
NC_017243:3093393:311378531137853114681897Brachyspira intermedia PWS/A chromosome, complete genomehypothetical protein2e-1583.2
NC_017243:2190000:220845822084582209387930Brachyspira intermedia PWS/A chromosome, complete genomehypothetical protein3e-1582.8
NC_010981:468465:490838490838491749912Wolbachia pipientis, complete genomehypothetical protein4e-1582.4
NC_012225:787737:809080809080810009930Brachyspira hyodysenteriae WA1, complete genomechromosome segregation ATPase5e-1582
NC_014150:1:546554656406942Brachyspira murdochii DSM 12563 chromosome, complete genomehypothetical protein1e-1480.9
NC_012225:1901656:191038119103811911277897Brachyspira hyodysenteriae WA1, complete genomehypothetical protein6e-1478.6
NC_014150:1123570:113012211301221130979858Brachyspira murdochii DSM 12563 chromosome, complete genomehypothetical protein1e-1377.4
NC_014150:1423758:143891514389151439850936Brachyspira murdochii DSM 12563 chromosome, complete genomehypothetical protein1e-1377.4
NC_010793:1922000:193167119316711932573903Orientia tsutsugamushi str. Ikeda, complete genomehypothetical protein4e-1375.5
NC_014150:1304573:130627013062701307202933Brachyspira murdochii DSM 12563 chromosome, complete genomehypothetical protein1e-1274.3
NC_012225:1775264:179129617912961792156861Brachyspira hyodysenteriae WA1, complete genomehypothetical protein9e-1374.3
NC_010793:541040:571027571027571953927Orientia tsutsugamushi str. Ikeda, complete genomehypothetical protein2e-1273.6
NC_014150:1936154:197251719725171973440924Brachyspira murdochii DSM 12563 chromosome, complete genome3e-1272.8
NC_010981:242500:286815286815287666852Wolbachia pipientis, complete genome5e-1272
NC_010793:1468849:147906814790681480066999Orientia tsutsugamushi str. Ikeda, complete genomehypothetical protein5e-1272
NC_010981:242500:248691248691249584894Wolbachia pipientis, complete genomehypothetical protein5e-1272
NC_015164:2935363:293779529377952938679885Bacteroides salanitronis DSM 18170 chromosome, complete genomehypothetical protein7e-1271.2
NC_010793:1723365:174602917460291746991963Orientia tsutsugamushi str. Ikeda, complete genomehypothetical protein8e-1271.2
NC_010793:357000:362529362529363467939Orientia tsutsugamushi str. Ikeda, complete genomehypothetical protein9e-1270.9
NC_010793:126111:141354141354141914561Orientia tsutsugamushi str. Ikeda, complete genomehypothetical protein3e-1169.3
NC_017243:314000:317373317373318074702Brachyspira intermedia PWS/A chromosome, complete genomehypothetical protein6e-1168.2
NC_002978:480707:492698492698493627930Wolbachia endosymbiont of Drosophila melanogaster, complete genomehypothetical protein8e-1167.8
NC_010981:1371265:141993014199301420850921Wolbachia pipientis, complete genomehypothetical protein8e-1167.8
NC_016001:2421580:243557724355772436449873Flavobacterium branchiophilum, complete genomehypothetical protein5e-0962
NC_016001:2421580:243466724346672435515849Flavobacterium branchiophilum, complete genomehypothetical protein7e-0961.6
NC_013061:2055000:206454420645442065446903Pedobacter heparinus DSM 2366, complete genomehypothetical protein4e-0859.3
NC_010263:563814:568602568602569172571Rickettsia rickettsii str. Iowa, complete genome3e-0859.3
NC_009883:1429000:143418414341841435023840Rickettsia bellii OSU 85-389, complete genomehypothetical protein3e-0859.3
NC_007940:97949:113175113175114014840Rickettsia bellii RML369-C, complete genomehypothetical protein3e-0859.3
NC_004663:2509433:254705225470522547966915Bacteroides thetaiotaomicron VPI-5482, complete genomehypothetical protein1e-0757.8
NC_016641:1984206:200206520020652002358294Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein2e-0653.9
NC_015565:1920329:193599619359961936568573Desulfotomaculum carboxydivorans CO-1-SRB chromosome, complete2e-0653.5
NC_020291:4357425:436810543681054368983879Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein6e-0652
NC_013165:2700978:270800027080002708971972Slackia heliotrinireducens DSM 20476, complete genomehypothetical protein6e-0651.6
NC_010793:1158279:115909311590931159950858Orientia tsutsugamushi str. Ikeda, complete genomehypothetical protein8e-0651.2