Pre_GI: BLASTP Hits

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Query: NC_015425:369225:369225 Clostridium botulinum BKT015925 chromosome, complete genome

Start: 369225, End: 372665, Length: 3441

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_021182:2360500:2363815236381523672793465Clostridium pasteurianum BC1, complete genomehelicase-exonuclease AddAB, AddB subunit01204
NC_016627:3972751:3978953397895339824263474Clostridium clariflavum DSM 19732 chromosome, complete genomeDNA helicase/exodeoxyribonuclease V subunit B01056
NC_014328:773095:7730957730957765473453Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative ATP-dependent nuclease subunit B01037
NC_004557:691944:7034027034027068753474Clostridium tetani E88, complete genomeATP-dependent nuclease subunit B01023
NC_020291:1:1865218652221283477Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeATP-dependent helicase/deoxyribonuclease subunit B0927
NC_009089:1202261:1224399122439912278663468Clostridium difficile 630, complete genomeATP-dependent nuclease subunit B0919
NC_013316:1081044:1103112110311211065793468Clostridium difficile R20291, complete genomeATP-dependent nuclease subunit B0918
NC_021184:3793285:3802339380233938059173579Desulfotomaculum gibsoniae DSM 7213, complete genomehelicase-exonuclease AddAB, AddB subunit0678
NC_003909:1244000:1251340125134012548553516Bacillus cereus ATCC 10987, complete genomeATP-dependent nuclease, subunit B0674
NC_011969:1181302:1188318118831811918333516Bacillus cereus Q1 chromosome, complete genomeATP-dependent nuclease, subunit b0672
NC_012659:1103737:1112039111203911155543516Bacillus anthracis str. A0248, complete genomeATP-dependent nuclease, subunit B0672
NC_005945:1103729:1112031111203111155463516Bacillus anthracis str. Sterne, complete genomeATP-dependent nuclease, subunit B0672
NC_014335:1094000:1101790110179011053053516Bacillus cereus biovar anthracis str. CI chromosome, completeATP-dependent nuclease subunit B0671
NC_011725:1150779:1159036115903611625513516Bacillus cereus B4264 chromosome, complete genomeATP-dependent nuclease subunit B0670
NC_011772:1094534:1102938110293811064533516Bacillus cereus G9842, complete genomeATP-dependent nuclease, subunit B0669
NC_007644:469181:4885524885524920073456Moorella thermoacetica ATCC 39073, complete genomeATP-dependent deoxyribonuclease subunit B0668
NC_014171:1118000:1124833112483311283483516Bacillus thuringiensis BMB171 chromosome, complete genomeATP-dependent nuclease subunit B0668
NC_017208:1147230:1155528115552811590433516Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeATP-dependent nuclease subunit B0667
NC_004722:1108649:1116979111697911204943516Bacillus cereus ATCC 14579, complete genomeATP-dependent nuclease subunit B0665
NC_010184:1114000:1118237111823711217523516Bacillus weihenstephanensis KBAB4, complete genomeATP-dependent nuclease subunit AddB0658
NC_014483:3498395:3510676351067635142453570Paenibacillus polymyxa E681 chromosome, complete genomeATP-dependent nuclease subunit B0650
NC_016641:5528826:5543785554378555473513567Paenibacillus terrae HPL-003 chromosome, complete genomeATP-dependent nuclease subunit B0644
NC_007907:1940000:1962315196231519659773663Desulfitobacterium hafniense Y51, complete genomehypothetical protein0644
NC_011830:3025437:3047848304784830515043657Desulfitobacterium hafniense DCB-2, complete genomeATP-dependent nuclease subunit B0642
NC_014622:3819495:3831345383134538349113567Paenibacillus polymyxa SC2 chromosome, complete genomeATP-dependent nuclease subunit b0640
NC_016047:1234743:1250727125072712542273501Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completeATP-dependent nuclease subunit B8e-180631
NC_014614:260782:2642142642142675703357Clostridium sticklandii, complete genomeATP-dependent deoxyribonuclease (subunit B)2e-155550
NC_013520:1905554:1916484191648419200413558Veillonella parvula DSM 2008, complete genomeATP-dependent nuclease subunit B-like protein9e-113409
NC_015978:1266196:1266196126619612697533558Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completeATP-dependent helicase/deoxyribonuclease subunit B2e-104380
NC_015428:2291430:2311828231182823153883561Lactobacillus buchneri NRRL B-30929 chromosome, complete genomeATP-dependent helicase/deoxyribonuclease subunit B5e-101370
NC_009785:1443500:1460513146051314637943282Streptococcus gordonii str. Challis substr. CH1, complete genomeputative exonuclease RexB6e-43177
NC_012440:1709416:1711423171142317141882766Persephonella marina EX-H1, complete genomehypothetical protein4e-0654.7