Pre_GI: BLASTP Hits

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Query: NC_015425:198315:212272 Clostridium botulinum BKT015925 chromosome, complete genome

Start: 212272, End: 213633, Length: 1362

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008593:196257:2075992075992089601362Clostridium novyi NT, complete genomeDNA repair protein RadA0844
NC_021182:4602683:4603775460377546051271353Clostridium pasteurianum BC1, complete genomeDNA repair protein RadA0675
NC_015687:3326461:3327546332754633288981353Clostridium acetobutylicum DSM 1731 chromosome, complete genomeDNA repair protein RadA0671
NC_003030:3324834:3325919332591933272711353Clostridium acetobutylicum ATCC 824, complete genomePredicted ATP-dependent serine protease, RADA homolog0671
NC_012658:3827500:3827505382750538288631359Clostridium botulinum Ba4 str. 657 chromosome, complete genomeDNA repair protein RadA0664
NC_014328:4471995:4471995447199544733501356Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeDNA repair protein RadA0651
NC_009699:3839575:3839575383957538409331359Clostridium botulinum F str. Langeland chromosome, complete genomeDNA repair protein RadA0647
NC_017297:3838189:3838189383818938395471359Clostridium botulinum F str. 230613 chromosome, complete genomeDNA repair protein RadA0647
NC_009698:3609881:3609881360988136112391359Clostridium botulinum A str. Hall chromosome, complete genomeDNA repair protein RadA0645
NC_009697:3711692:3712772371277237141301359Clostridium botulinum A str. ATCC 19397 chromosome, completeDNA repair protein RadA0645
NC_009495:3735703:3736783373678337381411359Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeDNA repair protein RadA0645
NC_010516:3807780:3807780380778038091381359Clostridium botulinum B1 str. Okra, complete genomeDNA repair protein radA0645
NC_012563:4004709:4004709400470940060671359Clostridium botulinum A2 str. Kyoto, complete genomeDNA repair protein RadA0644
NC_010520:3837378:3837378383737838387361359Clostridium botulinum A3 str. Loch Maree, complete genomeDNA repair protein radA0642
NC_008262:2598920:2647678264767826490391362Clostridium perfringens SM101, complete genomeDNA repair protein RadA0640
NC_011837:165913:1860441860441873991356Clostridium kluyveri NBRC 12016, complete genomeDNA repair protein RadA1e-180632
NC_009706:165913:1860441860441873991356Clostridium kluyveri DSM 555 chromosome, complete genomeDNA repair protein RadA1e-180632
NC_004557:2777291:2777291277729127786881398Clostridium tetani E88, complete genomeDNA repair protein radA7e-178623
NC_002570:126500:1375221375221388951374Bacillus halodurans C-125, complete genomeDNA repair protein9e-133473
NC_018704:81733:1118061118061131731368Amphibacillus xylanus NBRC 15112, complete genomeDNA repair protein RadA7e-132470
NC_011567:75306:9353593535949291395Anoxybacillus flavithermus WK1, complete genomeATP-dependent serine protease, RadA2e-131469
NC_017208:64500:1011481011481025241377Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeDNA repair protein RadA1e-128460
NC_010001:4250828:4257281425728142586391359Clostridium phytofermentans ISDg, complete genomeDNA repair protein RadA1e-126453
NC_010382:4479464:4491561449156144929371377Lysinibacillus sphaericus C3-41, complete genomeDNA repair protein radA-like protein (DNA repair protein sms-like protein)4e-126451
NC_012778:688621:6949536949536963321380Eubacterium eligens ATCC 27750, complete genomemethylated-DNA-[protein]-cysteine S-methyltransferase1e-124446
NC_009012:2100000:2106433210643321077971365Clostridium thermocellum ATCC 27405, complete genomeDNA repair protein RadA1e-123443
NC_013316:1:4532645326466991374Clostridium difficile R20291, complete genomeDNA repair protein8e-123440
NC_012673:1600242:1602157160215716035331377Exiguobacterium sp. AT1b, complete genomeDNA repair protein RadA8e-122437
NC_014378:131810:1489241489241503121389Acetohalobium arabaticum DSM 5501 chromosome, complete genomeDNA repair protein RadA2e-121436
NC_019970:336472:3514883514883528341347Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeDNA repair protein RadA3e-120432
NC_010999:2450974:2467458246745824688221365Lactobacillus casei, complete genomeDNA repair protein RadA3e-119429
NC_011899:86800:1067311067311080861356Halothermothrix orenii H 168, complete genomeDNA repair protein RadA3e-117422
NC_012781:2148478:2164835216483521662051371Eubacterium rectale ATCC 33656, complete genomeDNA repair protein RadA9e-117420
NC_015573:3167207:3167207316720731685711365Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomeDNA repair protein RadA7e-116417
NC_012108:442493:4628014628014641621362Desulfobacterium autotrophicum HRM2, complete genomeRadA4e-115415
NC_004461:277291:2876832876832890561374Staphylococcus epidermidis ATCC 12228, complete genomeradA protein3e-115415
NC_019903:421000:4310914310914324401350Desulfitobacterium dichloroeliminans LMG P-21439 chromosome,DNA repair protein RadA2e-114412
NC_007413:2312735:2328872232887223303951524Anabaena variabilis ATCC 29413, complete genomeDNA repair protein RadA6e-114411
NC_014926:1381152:1403967140396714052681302Thermovibrio ammonificans HB-1 chromosome, complete genomeDNA repair protein RadA1e-113410
NC_003272:4621554:4621554462155446230771524Nostoc sp. PCC 7120, complete genomeDNA repair protein2e-112405
NC_017079:1476887:1478429147842914797841356Caldilinea aerophila DSM 14535 = NBRC 104270, complete genomeDNA repair protein RadA6e-112404
NC_013894:117644:1421351421351434991365Thermocrinis albus DSM 14484 chromosome, complete genomeDNA repair protein RadA3e-111402
NC_006347:700838:7130147130147143811368Bacteroides fragilis YCH46, complete genomeputative DNA repair protein3e-111402
NC_003228:648669:6608456608456622121368Bacteroides fragilis NCTC 9343, complete genomeputative DNA repair protein3e-111402
NC_016776:701684:7164797164797178461368Bacteroides fragilis 638R, complete genomeputative DNA repair protein3e-111402
NC_015873:1487127:1487127148712714885061380Megasphaera elsdenii DSM 20460, complete genomeDNA repair protein radA6e-111401
NC_007503:2098980:2102231210223121035651335Carboxydothermus hydrogenoformans Z-2901, complete genomeDNA repair protein RadA2e-110399
NC_015711:570910:5774205774205787871368Myxococcus fulvus HW-1 chromosome, complete genomeDNA repair protein RadA3e-110399
NC_014759:2438492:2502917250291725042811365Marivirga tractuosa DSM 4126 chromosome, complete genomeDNA repair protein rada6e-110398
NC_012440:373863:3825733825733839161344Persephonella marina EX-H1, complete genomeDNA repair protein RadA2e-108393
NC_014498:62891:7965579655809171263Streptococcus pneumoniae 670-6B chromosome, complete genomeDNA repair protein RadA4e-107388
NC_009802:1077926:1094607109460710959471341Campylobacter concisus 13826, complete genomeDNA repair protein RadA1e-106386
NC_016048:2055199:2070197207019720715911395Oscillibacter valericigenes Sjm18-20, complete genomeDNA repair protein RadA2e-106386
NC_014494:47049:6114261142624041263Streptococcus pneumoniae AP200 chromosome, complete genomeputative ATP-dependent serine protease2e-106386
NC_017192:1137724:1139532113953211408811350Arcobacter sp. L, complete genomeDNA repair protein RadA1e-104380
NC_009455:53000:5341853418548121395Dehalococcoides sp. BAV1 chromosome, complete genomeDNA repair protein RadA2e-104379
NC_007356:51080:5399953999553931395Dehalococcoides sp. CBDB1, complete genomeDNA repair protein RadA2e-104379
NC_013890:53538:5353853538549321395Dehalococcoides sp. GT chromosome, complete genomeDNA repair protein RadA2e-104379
NC_012115:1415827:1437592143759214388961305Nautilia profundicola AmH, complete genomeDNA repair protein RadA3e-104379
NC_016940:3632974:3646565364656536479591395Saprospira grandis str. Lewin chromosome, complete genomeDNA repair protein RadA7e-104377
NC_007508:1446526:1470595147059514719861392Xanthomonas campestris pv. vesicatoria str. 85-10, complete genomeDNA repair protein4e-103375
NC_009714:1118500:1118587111858711199301344Campylobacter hominis ATCC BAA-381, complete genomeDNA repair protein RadA4e-102372
NC_015167:1154497:1177631117763111789921362Cellulophaga lytica DSM 7489 chromosome, complete genomeDNA repair protein RadA2e-101369
NC_005070:2133380:2144865214486521462591395Synechococcus sp. WH 8102, complete genomeputative DNA repair protein RadA3e-101369
NC_014618:4010689:4030542403054240319271386Enterobacter cloacae SCF1 chromosome, complete genomeDNA repair protein RadA8e-101367
NC_010519:416658:4177114177114190871377Haemophilus somnus 2336 chromosome, complete genomeDNA repair protein RadA1e-100367
NC_020260:3277007:3295120329512032965021383Cronobacter sakazakii Sp291, complete genomeDNA repair protein RadA2e-100366
NC_013282:646569:6465696465696479511383Cronobacter turicensis, complete genomeDNA repair protein radA3e-100365
NC_010943:1379707:1400584140058414019601377Stenotrophomonas maltophilia K279a, complete genomeputative DNA repair protein RadA (DNA repair protein SMS)6e-100364
NC_011297:1296968:1304122130412213054951374Dictyoglomus thermophilum H-6-12, complete genomeDNA repair protein RadA2e-99363
NC_010995:1459831:1479048147904814804181371Cellvibrio japonicus Ueda107, complete genomeDNA repair protein RadA2e-98360
NC_011565:69427:7219472194735611368Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,DNA repair protein RadA3e-98358
NC_014150:2924158:2946810294681029481921383Brachyspira murdochii DSM 12563 chromosome, complete genomeDNA repair protein RadA4e-98358
NC_009879:475500:4900594900594913991341Rickettsia canadensis str. McKiel, complete genomeDNA repair protein RadA1e-97357
NC_016929:474000:4893734893734907131341Rickettsia canadensis str. CA410 chromosome, complete genomeDNA repair protein RadA2e-97356
NC_017058:671000:6853006853006866401341Rickettsia australis str. Cutlack chromosome, complete genomeDNA repair protein RadA4e-96352
NC_014221:2392150:2397697239769723990431347Truepera radiovictrix DSM 17093 chromosome, complete genomeDNA repair protein RadA2e-95350
NC_016050:771752:7717527717527730861335Rickettsia japonica YH, complete genomeDNA repair protein radA3e-95348
NC_015866:767790:7677907677907691241335Rickettsia heilongjiangensis 054 chromosome, complete genomeDNA repair protein RadA5e-95348
NC_007799:284058:2912542912542926061353Ehrlichia chaffeensis str. Arkansas, complete genomeDNA repair protein RadA7e-95348
NC_012730:131445:1314451314451327791335Rickettsia peacockii str. Rustic, complete genomeDNA repair protein RadA1e-94347
NC_010263:771901:7719017719017732351335Rickettsia rickettsii str. Iowa, complete genomeDNA repair protein9e-95347
NC_016909:771542:7715427715427728761335Rickettsia rickettsii str. Arizona chromosome, complete genomeDNA repair protein RadA9e-95347
NC_016911:771916:7719167719167732501335Rickettsia rickettsii str. Hauke chromosome, complete genomeDNA repair protein RadA9e-95347
NC_016914:772025:7720257720257733591335Rickettsia rickettsii str. Hino chromosome, complete genomeDNA repair protein RadA9e-95347
NC_009881:724269:7278157278157291551341Rickettsia akari str. Hartford, complete genomepredicted repair protein3e-94346
NC_017066:683000:6830356830356843721338Rickettsia typhi str. TH1527 chromosome, complete genomeDNA repair protein RadA6e-93341
NC_006142:683000:6830236830236843601338Rickettsia typhi str. Wilmington, complete genomeDNA repair protein RadA6e-93341
NC_000963:676000:6771346771346784801347Rickettsia prowazekii str. Madrid E, complete genomeDNA REPAIR PROTEIN RADA HOMOLOG (radA)7e-92338
NC_017048:1018000:1019303101930310206491347Rickettsia prowazekii str. GvV257 chromosome, complete genomeDNA repair protein RadA7e-92338
NC_017050:676000:6771306771306784761347Rickettsia prowazekii str. Katsinyian chromosome, complete genomeDNA repair protein RadA7e-92338
NC_017056:678450:6771076771076784531347Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomeDNA repair protein RadA7e-92338
NC_017049:675261:6752616752616766071347Rickettsia prowazekii str. Chernikova chromosome, complete genomeDNA repair protein RadA4e-92338
NC_017051:674000:6752736752736766191347Rickettsia prowazekii str. Dachau chromosome, complete genomeDNA repair protein RadA4e-92338
NC_009778:3287693:3304211330421133054851275Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein3e-89329
NC_013939:1812259:1826558182655818278861329Deferribacter desulfuricans SSM1, complete genomeDNA repair protein RadA3e-88326
NC_012751:1190206:1211828121182812132101383Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeDNA repair/recombination protein2e-88326
NC_015514:3911655:3930433393043339318601428Cellulomonas fimi ATCC 484 chromosome, complete genomeDNA repair protein RadA8e-88324
NC_010531:428000:4429744429744442421269Polynucleobacter necessarius STIR1, complete genomeDNA repair protein RadA4e-86318
NC_015500:484984:5139565139565153441389Treponema brennaborense DSM 12168 chromosome, complete genomeDNA repair protein RadA5e-86318
NC_015499:352934:3551383551383565081371Thermodesulfobium narugense DSM 14796 chromosome, complete genomeDNA repair protein RadA3e-85316
NC_015275:3243689:3262142326214232635391398Clostridium lentocellum DSM 5427 chromosome, complete genomeDNA repair protein RadA4e-80298
NC_009617:163466:1634661634661648421377Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeDNA repair protein RadA4e-72272
NC_016012:977357:99932999932910007141386Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeDNA repair protein RadA1e-70267
NC_011295:779569:7870627870627882851224Coprothermobacter proteolyticus DSM 5265, complete genomeDNA repair protein RadA3e-58226
NC_014654:2138794:2139935213993521413071373Halanaerobium sp. 'sapolanicus' chromosome, complete genome2e-50200
NC_015757:263938:287335287335288027693Sulfobacillus acidophilus TPY chromosome, complete genomeDNA repair protein RadA2e-41170
NC_015757:263938:285989285989286549561Sulfobacillus acidophilus TPY chromosome, complete genomeDNA repair protein RadA7e-36151
NC_014408:1340016:1360501136050113619101410Methanothermobacter marburgensis str. Marburg chromosome, completeKaiC-related protein2e-0860.8