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Query: NC_015417:39633 Clostridium botulinum BKT015925 plasmid p1BKT015925, complete

Start: 39633, End: 62723, Length: 23091

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_014376:2964731*2964731300604241312Clostridium saccharolyticum WM1 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_010381:920009200011419722198Lysinibacillus sphaericus C3-41 plasmid pBsph, complete sequence1e-1179.8BLASTN svgBLASTP svg
NC_004557:45589545589547680920915Clostridium tetani E88, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_021171:4367834*4367834439037922546Bacillus sp. 1NLA3E, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_020410:33269443326944335777930836Bacillus amyloliquefaciens subsp. plantarum UCMB5036 complete3e-0971.9BLASTN svgBLASTP svg
NC_006958:18728491872849189317920331Corynebacterium glutamicum ATCC 13032, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_003450:18713771871377190288331507Corynebacterium glutamicum ATCC 13032, complete genome7e-0763.9BLASTN svgBLASTP svg