Pre_GI: BLASTP Hits

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Query: NC_014560:518582:543601 Helicobacter pylori SJM180 chromosome, complete genome

Start: 543601, End: 544506, Length: 906

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This strain was isolated from an Amerindian resident of San Juan Miraflores shantytown in Lima Peru with gastritis. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017354:848500:869709869709870614906Helicobacter pylori 52 chromosome, complete genomeGTP-binding protein Era2e-163575
NC_017360:1052473:107363310736331074538906Helicobacter pylori 35A chromosome, complete genomeGTP-binding protein Era3e-163574
NC_014256:683384:710375710375711280906Helicobacter pylori B8 chromosome, complete genomeGTP-binding protein Era1e-162572
NC_017359:813500:834171834171835076906Helicobacter pylori Sat464 chromosome, complete genomeGTP-binding protein Era1e-160565
NC_017368:852490:873336873336874241906Helicobacter pylori F16, complete genomeGTP-binding protein Era4e-160563
NC_017063:775337:791101791101792006906Helicobacter pylori ELS37 chromosome, complete genomeGTPase Era1e-159561
NC_017365:848500:869916869916870821906Helicobacter pylori F30, complete genomeGTP-binding protein Era2e-159561
NC_017357:495213:495213495213496118906Helicobacter pylori 908 chromosome, complete genomeGTP-binding protein9e-159559
NC_017372:855384:876338876338877243906Helicobacter pylori India7 chromosome, complete genomeGTP-binding protein Era1e-158559
NC_017375:872478:893326893326894231906Helicobacter pylori 83 chromosome, complete genomeGTP-binding protein Era5e-158556
NC_014935:711765:718502718502719410909Nitratifractor saLSUginis DSM 16511 chromosome, complete genomegtp-binding protein era2e-80298
NC_017187:1564403:157013415701341571018885Arcobacter butzleri ED-1, complete genomeGTP-binding protein Era1e-67256
NC_009802:931129:954089954089954958870Campylobacter concisus 13826, complete genomeGTP-binding protein Era4e-64244
NC_012880:3241886:325310232531023254007906Dickeya dadantii Ech703, complete genomeGTP-binding protein Era1e-44180
NC_011080:2722492:272397527239752724880906Salmonella enterica subsp. enterica serovar Newport str. SL254,GTP-binding protein Era4e-43175
NC_003197:2720726:272392527239252724830906Salmonella typhimurium LT2, complete genomeGTP-binding protein Era4e-43175
NC_016810:2719779:272164227216422722547906Salmonella enterica subsp. enterica serovar Typhimurium strGTP-binding protein era4e-43175
NC_016856:2773995:277547827754782776383906Salmonella enterica subsp. enterica serovar Typhimurium str. 14028SGTP-binding protein Era4e-43175
NC_016857:2719779:272164227216422722547906Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74GTP-binding protein Era4e-43175
NC_016860:2716152:271935127193512720256906Salmonella enterica subsp. enterica serovar Typhimurium strGTP-binding protein Era4e-43175
NC_016863:2721826:272368927236892724594906Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1GTP-binding protein Era4e-43175
NC_017046:2717810:272100927210092721914906Salmonella enterica subsp. enterica serovar Typhimurium str. 798GTP-binding protein era4e-43175
NC_013941:3182576:320541332054133206318906Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeGTP-binding protein era8e-43174
NC_012912:1229333:123297612329761233881906Dickeya zeae Ech1591, complete genomeGTP-binding protein Era4e-42172
NC_012440:585568:601083601083602000918Persephonella marina EX-H1, complete genomeGTP-binding protein Era5e-41168
NC_011565:469962:491915491915492817903Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,GTP-binding protein Era4e-40165
NC_015277:380624:399681399681400559879Sphingobacterium sp. 21 chromosome, complete genomeGTP-binding protein Era-like-protein6e-40164
NC_011999:1320159:132234113223411323243903Macrococcus caseolyticus JCSC5402, complete genomehypothetical protein3e-38159
NC_013895:1086500:1104674110467411063651692Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, completeGTP-binding protein Era3e-38159
NC_007298:2170181:218205821820582182942885Dechloromonas aromatica RCB, complete genomeGTP-binding protein Era1e-37157
NC_014734:353159:356539356539357420882Paludibacter propionicigenes WB4 chromosome, complete genomeGTP-binding protein era1e-37156
NC_013517:1849912:187630218763021877183882Sebaldella termitidis ATCC 33386, complete genomeGTP-binding protein Era2e-37156
NC_016808:1335087:133860513386051339525921Pasteurella multocida 36950 chromosome, complete genomeGTP-binding protein Era5e-37155
NC_008600:4101748:410174841017484102653906Bacillus thuringiensis str. Al Hakam, complete genomeGTP-binding protein4e-37155
NC_012472:4119192:411919241191924120097906Bacillus cereus 03BB102, complete genomeGTP-binding protein Era4e-37155
NC_011658:4107501:410750141075014108406906Bacillus cereus AH187 chromosome, complete genomeGTP-binding protein Era4e-37155
NC_011969:4001489:400258940025894003494906Bacillus cereus Q1 chromosome, complete genomeGTP-binding protein era4e-37155
NC_016771:4059445:406128540612854062190906Bacillus cereus NC7401, complete genomeGTP-binding protein Era4e-37155
NC_013947:4917711:492912849291284930024897Stackebrandtia nassauensis DSM 44728 chromosome, complete genomeGTP-binding protein Era4e-37155
NC_020291:1014333:103418910341891035079891Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeGTPase Era3e-37155
NC_010830:1451887:145541514554151456305891Candidatus Amoebophilus asiaticus 5a2, complete genomehypothetical protein6e-37154
NC_015144:1333179:135089413508941351781888Weeksella virosa DSM 16922 chromosome, complete genomeGTP-binding protein Era-like-protein4e-36152
NC_009674:3073564:307356430735643074469906Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeGTP-binding protein Era3e-36152
NC_015311:294283:308036308036308917882Prevotella denticola F0289 chromosome, complete genomeribosome biogenesis GTPase Era3e-36152
NC_017027:1329708:133478513347851335705921Pasteurella multocida subsp. multocida str. HN06 chromosome,GTP-binding protein Era2e-36152
NC_019960:1362370:136501613650161365897882Prevotella dentalis DSM 3688 chromosome 1, complete sequenceGTP-binding protein Era7e-36151
NC_013171:342714:375448375448376329882Anaerococcus prevotii DSM 20548, complete genomeGTP-binding protein Era1e-35150
NC_014933:270000:275123275123276004882Bacteroides helcogenes P 36-108 chromosome, complete genomeGTP-binding protein Era6e-35147
NC_015318:1583839:160249516024951603388894Hippea maritima DSM 10411 chromosome, complete genomeGTP-binding protein Era-like-protein7e-35147
NC_013198:1538792:156710715671071568009903Lactobacillus rhamnosus GG, complete genomeSmall GTP-binding protein domain:GTP-binding:GTP-binding protein Era1e-34147
NC_021150:1322000:133960513396051340507903Azotobacter vinelandii CA6, complete genomeGTP-binding protein Era2e-34146
NC_012560:1322000:133959313395931340495903Azotobacter vinelandii DJ, complete genomeGTP-binding protein Era2e-34146
NC_012004:470492:473188473188474087900Streptococcus uberis 0140J, complete genomeGTP-binding protein Era homolog1e-34146
NC_012470:580373:584455584455585351897Streptococcus equi subsp. zooepidemicus, complete genomeGTP-binding protein Era homolog2e-34145
NC_009718:731670:733908733908734813906Fervidobacterium nodosum Rt17-B1, complete genomeGTP-binding protein Era4e-34145
NC_011898:649000:670501670501671397897Clostridium cellulolyticum H10, complete genomeGTP-binding protein Era5e-34145
NC_007519:3527207:354804435480443548970927Desulfovibrio alaskensis G20 chromosome, complete genomeGTP-binding protein Era1e-33143
NC_011661:1332309:134349913434991344395897Dictyoglomus turgidum DSM 6724, complete genomeGTP-binding protein Era1e-33143
NC_009698:3006500:300673230067323007622891Clostridium botulinum A str. Hall chromosome, complete genomeGTP-binding protein Era3e-33142
NC_008054:1030994:106021110602111061116906Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, completeGTP-binding protein5e-33141
NC_008529:1042220:107852810785281079433906Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365, completeGTPase5e-33141
NC_014393:1782811:178409517840951784985891Clostridium cellulovorans 743B chromosome, complete genomeGTP-binding protein Era1e-32140
NC_004663:4977635:499075549907554991636882Bacteroides thetaiotaomicron VPI-5482, complete genomeputative GTP-binding protein3e-32139
NC_002944:2373873:237547723754772376376900Mycobacterium avium subsp. paratuberculosis K-10, complete genomeGTP-binding protein Era7e-32137
NC_009633:3055413:305883630588363059723888Alkaliphilus metalliredigens QYMF chromosome, complete genomeGTP-binding protein Era3e-31135
NC_010612:4501414:452204645220464522948903Mycobacterium marinum M, complete genomeGTP-binding protein Era1e-30133
NC_016001:2980245:300179630017963002677882Flavobacterium branchiophilum, complete genomeGTP-binding protein Era1e-30133
NC_015848:2684275:270438427043842705286903Mycobacterium canettii CIPT 140010059, complete genomeputative GTP-binding protein ERA8e-30130
NC_009525:2635792:265773926577392658641903Mycobacterium tuberculosis H37Ra, complete genomeGTP-binding protein Era8e-30130
NC_002932:296557:300491300491301408918Chlorobium tepidum TLS, complete genomeGTP-binding protein, Era/ThdF family3e-29129
NC_010673:703816:706297706297707169873Borrelia hermsii DAH, complete genomehypothetical protein8e-29127
NC_014958:843456:843456843456844364909Deinococcus maricopensis DSM 21211 chromosome, complete genomeGTP-binding protein Era-like-protein1e-28127
NC_006156:685344:701959701959702831873Borrelia garinii PBi chromosome linear, complete sequenceGTP-binding protein1e-28127
NC_005835:1773482:177654617765461777451906Thermus thermophilus HB27, complete genomeGTP-binding protein era1e-27123
NC_018721:865530:865530865530866351822Psychroflexus torquis ATCC 700755 chromosome, complete genomeGTP-binding protein Era7e-24111
NC_016633:2688144:270794627079462708827882Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomeGTP-binding protein Era1e-21103
NC_008710:703740:703740703740704612873Borrelia turicatae 91E135, complete genomeGTP-binding protein era-like2e-20100
NC_008025:2211813:2211813221181322131381326Deinococcus geothermalis DSM 11300, complete genomeSmall GTP-binding protein domain1e-0860.8
NC_014150:1607873:1627073162707316285271455Brachyspira murdochii DSM 12563 chromosome, complete genomeribosome-associated GTPase EngA2e-0860.1