Pre_GI: BLASTP Hits

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Query: NC_014560:518582:541728 Helicobacter pylori SJM180 chromosome, complete genome

Start: 541728, End: 542270, Length: 543

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This strain was isolated from an Amerindian resident of San Juan Miraflores shantytown in Lima Peru with gastritis. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017063:775337:793337793337793879543Helicobacter pylori ELS37 chromosome, complete genomeATP-dependent protease subunit HslV2e-100364
NC_017372:855384:878574878574879116543Helicobacter pylori India7 chromosome, complete genomeATP-dependent protease peptidase subunit3e-98357
NC_014256:683384:708502708502709044543Helicobacter pylori B8 chromosome, complete genomeprotein HslV1e-97355
NC_017359:813500:836407836407836949543Helicobacter pylori Sat464 chromosome, complete genomeATP-dependent protease peptidase subunit2e-97354
NC_017354:848500:871945871945872487543Helicobacter pylori 52 chromosome, complete genomeATP-dependent protease peptidase subunit6e-97352
NC_017375:872478:895562895562896104543Helicobacter pylori 83 chromosome, complete genomeATP-dependent protease HslVU7e-97352
NC_017360:1052473:107586910758691076411543Helicobacter pylori 35A chromosome, complete genomeATP-dependent protease HslVU7e-97352
NC_017368:852490:875572875572876114543Helicobacter pylori F16, complete genomeATP-dependent protease peptidase subunit2e-96350
NC_017365:848500:872152872152872694543Helicobacter pylori F30, complete genomeATP-dependent protease peptidase subunit9e-96348
NC_009802:931129:952228952228952761534Campylobacter concisus 13826, complete genome50S ribosomal protein L212e-67254
NC_017187:937649:941856941856942392537Arcobacter butzleri ED-1, complete genomeATP-dependent protease peptidase subunit5e-66249
NC_009850:972692:976899976899977435537Arcobacter butzleri RM4018, complete genomeheat shock protein HslVU, ATP-dependent protease subunit HslV5e-66249
NC_014624:2297000:231760523176052318138534Eubacterium limosum KIST612 chromosome, complete genome20S proteasome A and B2e-47188
NC_007912:3403101:342371334237133424252540Saccharophagus degradans 2-40, complete genomeDihydrodipicolinate reductase3e-46184
NC_007298:219783:219250219250219786537Dechloromonas aromatica RCB, complete genomeATP-dependent protease peptidase subunit6e-46183
NC_005945:3636321:364609336460933646635543Bacillus anthracis str. Sterne, complete genomeATP-dependent protease peptidase subunit5e-45180
NC_005957:3665657:366707136670713667613543Bacillus thuringiensis serovar konkukian str. 97-27, completeATP-dependent protease peptidase subunit5e-45180
NC_014335:3589726:359625235962523596794543Bacillus cereus biovar anthracis str. CI chromosome, completeATP-dependent protease peptidase subunit5e-45180
NC_003997:3617000:364539836453983645940543Bacillus anthracis str. Ames, complete genomeATP-dependent protease peptidase subunit5e-45180
NC_007530:3616828:364552536455253646067543Bacillus anthracis str. 'Ames Ancestor', complete genomeATP-dependent protease peptidase subunit5e-45180
NC_012581:559182:592620592620593162543Bacillus anthracis str. CDC 684 chromosome, complete genomeATP-dependent protease peptidase subunit5e-45180
NC_012659:3617000:364542536454253645967543Bacillus anthracis str. A0248, complete genomeATP-dependent protease peptidase subunit5e-45180
NC_014836:497350:516632516632517159528Desulfurispirillum indicum S5 chromosome, complete genome20S proteasome subunits A/B3e-45180
NC_002942:675829:678519678519679067549Legionella pneumophila subsp. pneumophila str. Philadelphia 1,heat shock protein, HslVU, proteasome-related peptidase subunit1e-44179
NC_009494:775676:775676775676776224549Legionella pneumophila str. Corby chromosome, complete genomeATP-dependent protease peptidase subunit1e-44179
NC_014125:766576:766576766576767124549Legionella pneumophila 2300/99 Alcoy chromosome, complete genomeheat shock protein1e-44179
NC_003909:3606177:362079636207963621338543Bacillus cereus ATCC 10987, complete genomeATP-dependent protease peptidase subunit1e-44179
NC_011658:3603009:363344336334433633985543Bacillus cereus AH187 chromosome, complete genomeATP-dependent protease peptidase subunit1e-44179
NC_011969:3575988:357740235774023577944543Bacillus cereus Q1 chromosome, complete genomeATP-dependent protease peptidase subunit8e-45179
NC_011772:3787500:381583338158333816375543Bacillus cereus G9842, complete genomeATP-dependent protease hslV6e-45179
NC_017208:3816753:384550938455093846051543Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeATP-dependent protease peptidase subunit6e-45179
NC_007645:6096345:611704661170466117591546Hahella chejuensis KCTC 2396, complete genomeATP-dependent protease HslVU (ClpYQ), peptidase subunit2e-44177
NC_019978:625476:627561627561628088528Halobacteroides halobius DSM 5150, complete genomeATP-dependent protease HslVU, peptidase subunit7e-44176
NC_014758:1546898:156595615659561566483528Calditerrivibrio nitroreducens DSM 19672 chromosome, completehslv component of hsluv peptidase1e-43176
NC_010718:1454087:145639214563921456937546Natranaerobius thermophilus JW/NM-WN-LF, complete genomeCodW component of CodWX peptidase. Threonine peptidase. MEROPS family T01B1e-43175
NC_014972:2771902:277136627713662771905540Desulfobulbus propionicus DSM 2032 chromosome, complete genomeATP dependent peptidase CodWX, CodW component1e-43175
NC_012489:2913920:293633529363352936880546Gemmatimonas aurantiaca T-27, complete genomeATP-dependent protease HslV2e-43174
NC_013960:2440453:244222424422242442763540Nitrosococcus halophilus Nc4 chromosome, complete genome20S proteasome A and B subunits3e-43174
NC_004461:921364:930719930719931261543Staphylococcus epidermidis ATCC 12228, complete genomeATP-dependent protease peptidase subunit3e-43174
NC_011901:39215:554445544455977534Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completeATP-dependent protease peptidase subunit1e-42172
NC_007168:1705763:171482117148211715366546Staphylococcus haemolyticus JCSC1435, complete genomeATP-dependent protease peptidase subunit2e-42171
NC_014652:628435:631856631856632386531Caldicellulosiruptor hydrothermalis 108 chromosome, complete20S proteasome a and b subunits5e-42170
NC_002937:1634287:165921416592141659759546Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completeATP-dependent protease peptidase subunit5e-42170
NC_014377:1060000:106780110678011068331531Thermosediminibacter oceani DSM 16646 chromosome, complete genomeATP dependent peptidase CodWX, CodW component1e-41169
NC_018419:862500:884893884893885465573Secondary endosymbiont of Ctenarytaina eucalypti chromosome,ATP-dependent protease HslVU, peptidase subunit8e-42169
NC_014721:434501:447187447187447717531Caldicellulosiruptor kristjanssonii 177R1B chromosome, complete20S proteasome a and b subunits6e-42169
NC_014926:295988:302673302673303203531Thermovibrio ammonificans HB-1 chromosome, complete genome20S proteasome A and B subunits5e-41166
NC_014216:1197704:122724212272421227772531Desulfurivibrio alkaliphilus AHT2 chromosome, complete genome20S proteasome A and B subunits9e-41166
NC_014171:3726054:372937437293743729835462Bacillus thuringiensis BMB171 chromosome, complete genomeATP-dependent protease peptidase1e-40165
NC_015593:797675:810670810670811212543Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeATP-dependent protease hslV6e-40163
NC_004347:4302768:433533143353314335855525Shewanella oneidensis MR-1, complete genomeATP-dependent protease peptidase subunit7e-40163
NC_016751:1604048:162264216226421623175534Marinitoga piezophila KA3 chromosome, complete genomeATP-dependent protease HslVU, peptidase subunit1e-38159
NC_012985:410307:419913419913420485573Candidatus Liberibacter asiaticus str. psy62, complete genomeATP-dependent protease peptidase subunit1e-38159
NC_010939:1986263:199724419972441997765522Actinobacillus pleuropneumoniae serovar 7 str. AP76, completeATP-dependent protease hslV8e-39159
NC_009053:1942973:197236119723611972882522Actinobacillus pleuropneumoniae L20, complete genomeATP-dependent protease hslV8e-39159
NC_010278:1918000:193389819338981934419522Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,ATP-dependent protease peptidase subunit8e-39159
NC_009952:3596399:362402436240243624581558Dinoroseobacter shibae DFL 12, complete genomeATP-dependent HslUV protease5e-38157
NC_011244:319373:327026327026327568543Borrelia recurrentis A1, complete genomeATP-dependent protease peptidase subunit7e-38156
NC_015185:1114180:111867511186751119208534Desulfurobacterium thermolithotrophum DSM 11699 chromosome,ATP-dependent protease hslV7e-38156
NC_009257:963536:983051983051983602552Francisella tularensis subsp. tularensis WY96-3418 chromosome,ATP-dependent protease peptidase subunit2e-37155
NC_014355:243543:261488261488262024537Candidatus Nitrospira defluvii, complete genomeheat shock protein hslUV, peptidase component3e-37154
NC_017238:272980:304226304226304774549Borrelia afzelii PKo chromosome, complete genomeATP-dependent protease subunit HslV3e-37154
NC_014774:293800:303778303778304347570Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completeATP-dependent protease peptidase subunit2e-37154
NC_008710:277207:307098307098307640543Borrelia turicatae 91E135, complete genomeATP-dependent protease HslV7e-37153
NC_007794:2839239:287213528721352872692558Novosphingobium aromaticivorans DSM 12444, complete genome20S proteasome, A and B subunits1e-36152
NC_019907:1454554:146935214693521469912561Liberibacter crescens BT-1 chromosome, complete genomeATP-dependent protease HslV1e-36152
NC_010673:291679:307806307806308348543Borrelia hermsii DAH, complete genomeATP-dependent protease HslV1e-36152
NC_016629:2971860:297186029718602972396537Desulfovibrio africanus str. Walvis Bay chromosome, completeATP-dependent protease hslV2e-36151
NC_013199:1407742:142930914293091429833525Lactobacillus rhamnosus Lc 705, complete genomeATP-dependent protease, HslVU (ClpYQ) peptidase subunit5e-36150
NC_018145:1089548:110821911082191108773555Zymomonas mobilis subsp. mobilis ATCC 29191 chromosome, completeATP-dependent protease hslV8e-33139