Pre_GI: BLASTP Hits

Some Help

Query: NC_014560:518582:535405 Helicobacter pylori SJM180 chromosome, complete genome

Start: 535405, End: 536850, Length: 1446

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This strain was isolated from an Amerindian resident of San Juan Miraflores shantytown in Lima Peru with gastritis. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017360:1052473:1069570106957010710151446Helicobacter pylori 35A chromosome, complete genomecag pathogenicity island protein0758
NC_017378:502806:5028065028065042511446Helicobacter pylori Puno120 chromosome, complete genomecag pathogenicity island protein (cag delta, cag3)0758
NC_011333:514464:5147155147155161601446Helicobacter pylori G27 chromosome, complete genomecag pathogenicity island protein 30757
NC_017063:800156:8005928005928020371446Helicobacter pylori ELS37 chromosome, complete genomecag pathogenicity island protein Delta0757
NC_017355:493237:4938114938114952561446Helicobacter pylori v225d chromosome, complete genomecag pathogenicity island protein0756
NC_011498:553525:5535255535255549701446Helicobacter pylori P12, complete genomecag pathogenicity island protein Delta0756
NC_017375:872478:8892688892688907131446Helicobacter pylori 83 chromosome, complete genomecag pathogenicity island protein0756
NC_000915:547783:5481345481345495791446Helicobacter pylori 26695, complete genomecag pathogenicity island protein (cag3)0756
NC_018939:547793:5481445481445495891446Helicobacter pylori 26695 chromosome, complete genomecag pathogenicity island protein (cag3)0756
NC_017365:848500:8658548658548672991446Helicobacter pylori F30, complete genomecag pathogenicity island protein0755
NC_017379:505350:5057005057005071451446Helicobacter pylori Puno135 chromosome, complete genomecag pathogenicity island protein 30754
NC_017366:535188:5351885351885366331446Helicobacter pylori F32, complete genomecag pathogenicity island protein0754
NC_014256:683384:7005337005337019781446Helicobacter pylori B8 chromosome, complete genomecag pathogenicity island protein delta0754
NC_017367:562918:5629185629185643631446Helicobacter pylori F57, complete genomecag pathogenicity island protein0754
NC_017354:848500:8655998655998670441446Helicobacter pylori 52 chromosome, complete genomecag pathogenicity island protein 30753
NC_017368:852490:8692748692748707191446Helicobacter pylori F16, complete genomecag pathogenicity island protein0753
NC_008086:513407:5141585141585156031446Helicobacter pylori HPAG1, complete genomecag pathogenicity island protein 30752
NC_017358:563336:5633365633365647811446Helicobacter pylori Cuz20 chromosome, complete genomecag pathogenicity island protein (cag delta, cag3)0751
NC_017362:506950:5071955071955086401446Helicobacter pylori Lithuania75 chromosome, complete genomecag pathogenicity island protein 30750
NC_017376:538000:5397235397235411681446Helicobacter pylori SNT49 chromosome, complete genomecag pathogenicity island protein (cag3)0750
NC_017359:813500:8300498300498315781530Helicobacter pylori Sat464 chromosome, complete genomecag pathogenicity island protein (cag delta, cag3)0748
NC_017372:855384:8720008720008734391440Helicobacter pylori India7 chromosome, complete genomecag pathogenicity island protein 30747
NC_010698:819912:8428558428558443001446Helicobacter pylori Shi470, complete genomecag pathogenicity island protein (cag3)0746
NC_017381:500699:5006995006995021441446Helicobacter pylori 2018 chromosome, complete genomecag pathogenicity island protein0741
NC_017374:498588:4985884985885000331446Helicobacter pylori 2017 chromosome, complete genomecag pathogenicity island protein0741
NC_017357:495213:4994574994575009021446Helicobacter pylori 908 chromosome, complete genomecag pathogenicity island protein0740
NC_014555:502151:5021515021515035961446Helicobacter pylori PeCan4 chromosome, complete genomecag pathogenicity island protein (cag3)0732
NC_017371:530673:5306735306735321181446Helicobacter pylori Gambia94/24 chromosome, complete genomecag island protein0730
NC_000921:511642:5116425116425130871446Helicobacter pylori J99, complete genomecag island protein0729