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Query: NC_014335:5165211:5165211 Bacillus cereus biovar anthracis str. CI chromosome, complete

Start: 5165211, End: 5166503, Length: 1293

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015873:924392:9395999395999410051407Megasphaera elsdenii DSM 20460, complete genomehypothetical protein1e-70267
NC_008228:2068641:2076094207609420773831290Pseudoalteromonas atlantica T6c, complete genomehypothetical protein7e-53208
NC_014216:1197704:1212795121279512140721278Desulfurivibrio alkaliphilus AHT2 chromosome, complete genomeRNA-directed DNA polymerase (Reverse transcriptase)3e-50199
NC_020260:1293860:1304355130435513056411287Cronobacter sakazakii Sp291, complete genomehypothetical protein3e-48192
NC_009434:796878:8065888065888077721185Pseudomonas stutzeri A1501, complete genomehypothetical protein7e-47188
NC_015703:3842144:3854989385498938564671479Runella slithyformis DSM 19594 chromosome, complete genomeRNA-directed DNA polymerase2e-44180
NC_018721:943801:9612119612119627941584Psychroflexus torquis ATCC 700755 chromosome, complete genomeretron-type reverse transcriptase1e-42174
NC_014334:1848340:1862085186208518635001416Lactobacillus casei str. Zhang chromosome, complete genomehypothetical protein7e-38158
NC_014041:1395761:1412056141205614131291074Zunongwangia profunda SM-A87 chromosome, complete genomereverse transcriptase3e-0756.6
NC_012968:2000218:2009033200903320104991467Methylotenera mobilis JLW8, complete genomeRNA-directed DNA polymerase (Reverse transcriptase)5e-0755.8
NC_008209:1097607:110770411077041108630927Roseobacter denitrificans OCh 114, complete genomehypothetical protein1e-0654.7
NC_014171:261952:2642142642142653681155Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein2e-0653.9