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Query: NC_014335:4697293:4698531 Bacillus cereus biovar anthracis str. CI chromosome, complete

Start: 4698531, End: 4699058, Length: 528

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4745053:474505347450534745583531Bacillus anthracis str. A0248, complete genomeputative lipoprotein2e-85314
NC_003997:4745027:474502747450274745557531Bacillus anthracis str. Ames, complete genomelipoprotein, putative2e-85314
NC_007530:4744870:474515347451534745683531Bacillus anthracis str. 'Ames Ancestor', complete genomelipoprotein, putative2e-85314
NC_011772:4875893:489620748962074896734528Bacillus cereus G9842, complete genomeputative lipoprotein1e-81301
NC_018665:1233084:123997812399781240505528Exiguobacterium antarcticum B7 chromosome, complete genomelipoprotein9e-0856.2