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Query: NC_014335:3902155:3916649 Bacillus cereus biovar anthracis str. CI chromosome, complete

Start: 3916649, End: 3918175, Length: 1527

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011773:3982008:3999477399947740010031527Bacillus cereus AH820 chromosome, complete genomehypothetical protein0960
NC_006274:4031246:4045370404537040468961527Bacillus cereus E33L, complete genomeconserved hypothetical protein; possible hemagglutinin0960
NC_016779:3913627:3928657392865739301831527Bacillus cereus F837/76 chromosome, complete genomeHemagglutinin, Hemagglutinin0959
NC_008600:3976045:3993526399352639950521527Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein0959
NC_007530:3992228:4007254400725440087801527Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein0957
NC_003997:3993223:4007127400712740086531527Bacillus anthracis str. Ames, complete genomehypothetical protein0957
NC_005945:3992600:4007626400762640091521527Bacillus anthracis str. Sterne, complete genomehypothetical protein0957
NC_012659:3992684:4007154400715440086801527Bacillus anthracis str. A0248, complete genomehypothetical protein0957
NC_005957:3975192:3993730399373039952561527Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein0880
NC_020134:2067476:2067476206747620689391464Clostridium stercorarium subsp. stercorarium DSM 8532, completehypothetical protein1e-0758.5
NC_014721:373607:3736073736073750431437Caldicellulosiruptor kristjanssonii 177R1B chromosome, completehypothetical protein3e-0653.5
NC_015949:2101302:2123953212395321253891437Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomehypothetical protein3e-0653.5
NC_008526:1973500:1979045197904519806221578Lactobacillus casei ATCC 334, complete genomehypothetical protein5e-0653.1
NC_015067:2136048:2146908214690821484941587Bifidobacterium longum subsp. longum JCM 1217, complete genomehypothetical protein6e-0652.8