Pre_GI: BLASTP Hits

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Query: NC_014335:2009662:2020534 Bacillus cereus biovar anthracis str. CI chromosome, complete

Start: 2020534, End: 2020815, Length: 282

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012581:2178000:218071421807142180995282Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein1e-32138
NC_012472:2109719:212829921282992128580282Bacillus cereus 03BB102, complete genomehypothetical protein2e-32137
NC_009674:840000:846279846279846938660Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein1e-1478.6
NC_006274:4031246:4047983404798340492781296Bacillus cereus E33L, complete genomehypothetical protein1e-0858.5
NC_014103:2635695:2647906264790626498401935Bacillus megaterium DSM319 chromosome, complete genometransposase family protein4e-0857