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Query: NC_014335:2009662:2009662 Bacillus cereus biovar anthracis str. CI chromosome, complete

Start: 2009662, End: 2012337, Length: 2676

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012472:2109719:2109719210971921123942676Bacillus cereus 03BB102, complete genomeTPR domain protein01734
NC_012581:2178000:2190269219026921916751407Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein0964
NC_012581:2178000:2188999218899921902791281Bacillus anthracis str. CDC 684 chromosome, complete genomeTPR domain-containing protein0828
NC_013156:154233:165112165112166050939Methanocaldococcus fervens AG86, complete genomeTPR repeat-containing protein5e-0757.4
NC_011296:1821244:1830831183083118340013171Thermodesulfovibrio yellowstonii DSM 11347, complete genometetratricopeptide repeat domain protein6e-0757