Pre_GI: BLASTP Hits

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Query: NC_014331:57769:83898 Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, complete

Start: 83898, End: 84449, Length: 552

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017203:73952:106495106495107046552Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281,hypothetical protein1e-97355
NC_012473:46000:692986929869849552Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein2e-92337
NC_012656:67949:838708387084334465Bacillus anthracis str. A0248 plasmid pXO1, complete sequence3e-89327
NC_012579:72715:839148391484378465Bacillus anthracis str. CDC 684 plasmid pX01, complete sequencehypothetical protein3e-89327
NC_007322:57710:836068360684070465Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completehypothetical protein3e-89327