Pre_GI: BLASTP Hits

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Query: NC_014331:57769:71529 Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, complete

Start: 71529, End: 71690, Length: 162

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012656:67949:717687176871929162Bacillus anthracis str. A0248 plasmid pXO1, complete sequencehypothetical protein1e-23108
NC_007322:57710:715047150471665162Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completehypothetical protein1e-23108
NC_012473:46000:560935609356254162Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein1e-22105