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Query: NC_014039:261126 Propionibacterium acnes SK137 chromosome, complete genome

Start: 261126, End: 287317, Length: 26192

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_013714:2350749*2350749237219321445Bifidobacterium dentium Bd1, complete genome8e-1383.8BLASTN svgBLASTP svg
NC_015671:31533253153325317759924275Cellvibrio gilvus ATCC 13127 chromosome, complete genome4e-24121BLASTN svgBLASTP svg
NC_008278:66702366702369009923077Frankia alni ACN14a, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_013729:380312*38031240421723906Kribbella flavida DSM 17836, complete genome2e-22115BLASTN svgBLASTP svg
NC_014815:2639339*2639339265728817950Micromonospora sp. L5 chromosome, complete genome1e-30143BLASTN svgBLASTP svg
NC_014210:56836165683616570702223407Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,2e-1075.8BLASTN svgBLASTP svg
NC_006085:23412723412725583521709Propionibacterium acnes KPA171202, complete genome024610BLASTN svgBLASTP svg
NC_009142:267550*26755029023122682Saccharopolyspora erythraea NRRL 2338, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_014168:86974686974691121841473Segniliparus rotundus DSM 44985 chromosome, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_010572:45054284505428452522719800Streptomyces griseus subsp. griseus NBRC 13350, complete genome4e-30141BLASTN svgBLASTP svg
NC_015953:3860467*3860467388114620680Streptomyces sp. SirexAA-E chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_007333:39579395797952139943Thermobifida fusca YX, complete genome1e-20109BLASTN svgBLASTP svg
NC_013510:54994475499447554883349387Thermomonospora curvata DSM 43183, complete genome3e-0971.9BLASTN svgBLASTP svg