Pre_GI: BLASTP Hits

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Query: NC_014039:499233:521040 Propionibacterium acnes SK137 chromosome, complete genome

Start: 521040, End: 521927, Length: 888

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:463460:485273485273486160888Propionibacterium acnes TypeIA2 P.acn33 chromosome, completehypothetical protein7e-146516
NC_006085:481231:5028905028905039301041Propionibacterium acnes KPA171202, complete genomehypothetical protein9e-146516
NC_016511:472666:494477494477495364888Propionibacterium acnes TypeIA2 P.acn31 chromosome, completehypothetical protein7e-146516