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Query: NC_014039:499233:505941 Propionibacterium acnes SK137 chromosome, complete genome

Start: 505941, End: 506705, Length: 765

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006085:481231:487939487939488703765Propionibacterium acnes KPA171202, complete genomemetal binding protein1e-143508
NC_016516:463460:470138470138470938801Propionibacterium acnes TypeIA2 P.acn33 chromosome, completemetal binding protein2e-143508
NC_016511:472666:479341479341480141801Propionibacterium acnes TypeIA2 P.acn31 chromosome, completemetal binding protein1e-142505
NC_016109:1305368:131737513173751318145771Kitasatospora setae KM-6054, complete genomehypothetical protein4e-57221
NC_008148:2498000:255009925500992550851753Rubrobacter xylanophilus DSM 9941, complete genomeperiplasmic binding protein7e-29127
NC_015966:2337833:234254823425482343354807Rhodothermus marinus SG0.5JP17-172 chromosome, complete genomeABC transporter periplasmic subunit8e-25114
NC_013501:931418:945153945153945959807Rhodothermus marinus DSM 4252, complete genomeperiplasmic binding protein8e-25114
NC_015703:4531578:453664145366414537429789Runella slithyformis DSM 19594 chromosome, complete genomeABC transporter periplasmic subunit3e-23108
NC_010718:2513917:252235825223582523326969Natranaerobius thermophilus JW/NM-WN-LF, complete genomeperiplasmic binding protein5e-0961.6
NC_015275:820723:8322618322618332621002Clostridium lentocellum DSM 5427 chromosome, complete genomeABC-type transporter, periplasmic subunit6e-0961.2
NC_007951:1042291:106546310654631066374912Burkholderia xenovorans LB400 chromosome 1, complete sequenceABC Fe3+-hydroxamate/cobalamin transporter, periplasmic ligand binding protein7e-0857.8
NC_014831:1557485:1558876155887615599131038Thermaerobacter marianensis DSM 12885 chromosome, complete genomeperiplasmic binding protein2e-0756.2
NC_000917:1246806:124587512458751246809935Archaeoglobus fulgidus DSM 4304, complete genomespermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein (potD)1e-0653.9
NC_014958:3346500:336923533692353370122888Deinococcus maricopensis DSM 21211 chromosome, complete genomeABC transporter periplasmic subunit2e-0653.1
NC_014623:9038177:905984190598419060704864Stigmatella aurantiaca DW4/3-1 chromosome, complete genomeiron-binding protein3e-0652.4