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Query: NC_014039:499233:505099 Propionibacterium acnes SK137 chromosome, complete genome

Start: 505099, End: 505944, Length: 846

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012488:1159463:116075811607581161504747Listeria monocytogenes Clip81459, complete genomecobalamin (5'-phosphatase) synthetase2e-0757
NC_012491:1263469:126851212685121269252741Brevibacillus brevis NBRC 100599, complete genomecobalamin (5'-phosphate) synthase9e-0650.8
NC_016148:141011:156052156052156792741Thermovirga lienii DSM 17291 chromosome, complete genomecobalamin 5'-phosphate synthase2e-0962.8
NC_019673:1656680:166097216609721661685714Saccharothrix espanaensis DSM 44229 complete genomeCobalamin 5'-phosphate synthase3e-1272.4
NC_009253:2927802:293128329312832932032750Desulfotomaculum reducens MI-1 chromosome, complete genomecobalamin 5'-phosphate synthase7e-0858.2
NC_016802:1615748:163378016337801634604825Corynebacterium diphtheriae HC02 chromosome, complete genomecobalamin synthase5e-0858.5
NC_017295:1507956:152574015257401526498759Clostridium acetobutylicum EA 2018 chromosome, complete genomecobalamin synthase5e-0652
NC_004369:2203947:222279922227992223626828Corynebacterium efficiens YS-314, complete genomecobalamin synthase4e-0858.9
NC_003030:1510000:152632615263261527084759Clostridium acetobutylicum ATCC 824, complete genomecobalamin synthase5e-0652
NC_015687:1508664:152792715279271528685759Clostridium acetobutylicum DSM 1731 chromosome, complete genomecobalamin synthase5e-0652
NC_016516:463460:469338469338470177840Propionibacterium acnes TypeIA2 P.acn33 chromosome, completecobalamin-5-phosphate synthase, CobS8e-110396
NC_016511:472666:478541478541479380840Propionibacterium acnes TypeIA2 P.acn31 chromosome, completecobalamin-5-phosphate synthase, CobS7e-110396
NC_013766:1202713:120271312027131203459747Listeria monocytogenes 08-5578 chromosome, complete genomehypothetical protein1e-0653.9
NC_006085:481231:487055487055487942888Propionibacterium acnes KPA171202, complete genomeputative cobalamin-5-phosphate synthase, CobS2e-110398