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Query: NC_013016:656000:675653 Neisseria meningitidis alpha14 chromosome, complete genome

Start: 675653, End: 676129, Length: 477

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017515:1527461:152746115274611527937477Neisseria meningitidis M04-240196 chromosome, complete genomechorismate--pyruvate lyase4e-74276
NC_017516:1535904:153925715392571539733477Neisseria meningitidis H44/76 chromosome, complete genomechorismate--pyruvate lyase3e-75280
NC_017514:1491235:149123514912351491711477Neisseria meningitidis M01-240149 chromosome, complete genomechorismate--pyruvate lyase5e-76282
NC_017518:828662:843072843072843548477Neisseria meningitidis NZ-05/33 chromosome, complete genomechorismate--pyruvate lyase5e-76282
NC_003112:744476:765557765557766033477Neisseria meningitidis MC58, complete genomehypothetical protein2e-77287
NC_017505:751836:769460769460769936477Neisseria meningitidis alpha710 chromosome, complete genomeputative 4-hydroxybenzoate synthetase7e-72268