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Query: NC_013016:656000:672772 Neisseria meningitidis alpha14 chromosome, complete genome

Start: 672772, End: 673257, Length: 486

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017518:828662:839914839914840399486Neisseria meningitidis NZ-05/33 chromosome, complete genomecytoplasmic membrane protein fxsA6e-63239
NC_017514:1491235:149438414943841494869486Neisseria meningitidis M01-240149 chromosome, complete genomecytoplasmic membrane protein fxsA6e-63239
NC_017515:1527461:153061015306101531095486Neisseria meningitidis M04-240196 chromosome, complete genomecytoplasmic membrane protein fxsA8e-63238
NC_003112:744476:762295762295762780486Neisseria meningitidis MC58, complete genomehypothetical protein4e-62236
NC_017505:751836:766197766197766682486Neisseria meningitidis alpha710 chromosome, complete genomeFxsA; putative membrane protein5e-62236
NC_017516:1535904:154251015425101542995486Neisseria meningitidis H44/76 chromosome, complete genomecytoplasmic membrane protein fxsA1e-61234