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Query: NC_013016:656000:672134 Neisseria meningitidis alpha14 chromosome, complete genome

Start: 672134, End: 672442, Length: 309

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017505:751836:765559765559765867309Neisseria meningitidis alpha710 chromosome, complete genomehypothetical protein2e-45181
NC_017518:828662:839294839294839584291Neisseria meningitidis NZ-05/33 chromosome, complete genomehypothetical protein2e-41167
NC_017514:1491235:149519914951991495489291Neisseria meningitidis M01-240149 chromosome, complete genomehypothetical protein2e-41167
NC_017516:1535904:154332515433251543615291Neisseria meningitidis H44/76 chromosome, complete genomehypothetical protein2e-41167
NC_017515:1527461:153142515314251531715291Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein2e-41167