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Query: NC_013016:419604:438266 Neisseria meningitidis alpha14 chromosome, complete genome

Start: 438266, End: 438724, Length: 459

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017517:527687:569005569005569463459Neisseria meningitidis M01-240355 chromosome, complete genomehypothetical protein8e-59225
NC_017501:1829500:183351118335111833969459Neisseria meningitidis 8013, complete genomehypothetical protein8e-59225
NC_017516:1755500:176102317610231761481459Neisseria meningitidis H44/76 chromosome, complete genomehypothetical protein5e-58222
NC_017515:1744500:174998117499811750439459Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein5e-58222
NC_017514:1721416:172534517253451725791447Neisseria meningitidis M01-240149 chromosome, complete genomehypothetical protein3e-56216