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Query: NC_013016:419604:425774 Neisseria meningitidis alpha14 chromosome, complete genome

Start: 425774, End: 426181, Length: 408

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017512:425085:433699433699434052354Neisseria meningitidis WUE 2594, complete genomehypothetical protein1e-42171
NC_003112:1824196:187192518719251872278354Neisseria meningitidis MC58, complete genomehypothetical protein1e-42171
NC_003116:658879:667772667772668125354Neisseria meningitidis Z2491, complete genomehypothetical protein3e-42170
NC_010120:452771:461229461229461582354Neisseria meningitidis 053442, complete genomeconserved hypothetical protein3e-42170
NC_008767:451983:458669458669459022354Neisseria meningitidis FAM18, complete genomehypothetical protein3e-42169