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Query: NC_012731:3593000:3600886 Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome

Start: 3600886, End: 3601521, Length: 636

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a liver abscess. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014618:2423661:243142324314232432109687Enterobacter cloacae SCF1 chromosome, complete genomehypothetical protein2e-54212
NC_015663:770485:786184786184786876693Enterobacter aerogenes KCTC 2190 chromosome, complete genomehypothetical protein8e-22103
NC_015761:1970042:199573219957321996418687Salmonella bongori NCTC 12419, complete genomehypothetical protein2e-0962.4
NC_013716:1918664:193766919376691938331663Citrobacter rodentium ICC168, complete genomehypothetical protein3e-0755.5
NC_011283:2684046:269962426996242700253630Klebsiella pneumoniae 342 chromosome, complete genomehypothetical protein1e-0653.1
NC_013850:2685835:270442027044202705049630Klebsiella variicola At-22 chromosome, complete genomeputative transcriptional regulator, Crp/Fnr family1e-0653.1