Pre_GI: BLASTN Hits

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Query: NC_012659:678289 Bacillus anthracis str. A0248, complete genome

Start: 678289, End: 696971, Length: 18683

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_007530:67426567426569315018886Bacillus anthracis str. 'Ames Ancestor', complete genome021400BLASTN svgBLASTP svg
NC_003997:67426567426569314918885Bacillus anthracis str. Ames, complete genome021400BLASTN svgBLASTP svg
NC_005945:67433767433769304518709Bacillus anthracis str. Sterne, complete genome021400BLASTN svgBLASTP svg
UCMB5137:28945112894511291649621986Bacillus atrophaeus UCMB-51371e-1075.8BLASTN svgBLASTP svg
NC_004722:65095065095066943618487Bacillus cereus ATCC 14579, complete genome015180BLASTN svgBLASTP svg
NC_006274:65992265992268275922838Bacillus cereus E33L, complete genome020280BLASTN svgBLASTP svg
NC_011772:64777864777866815320376Bacillus cereus G9842, complete genome015090BLASTN svgBLASTP svg
NC_009848:16137316137318435122979Bacillus pumilus SAFR-032, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_005957:66795466795469053422581Bacillus thuringiensis serovar konkukian str. 97-27, complete020880BLASTN svgBLASTP svg
NC_010184:66122666122668503723812Bacillus weihenstephanensis KBAB4, complete genome013050BLASTN svgBLASTP svg
NC_010674:65859665859667712118526Clostridium botulinum B str. Eklund 17B, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_010723:62292862292864247719550Clostridium botulinum E3 str. Alaska E43, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_008593:2020473*2020473204359923127Clostridium novyi NT, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_015703:75417275417278042826257Runella slithyformis DSM 19594 chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_014538:187747*18774720633818592Thermoanaerobacter sp. X513 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg