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Query: NC_012659:678289:688781 Bacillus anthracis str. A0248, complete genome

Start: 688781, End: 691180, Length: 2400

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003997:674265:6888806888806912792400Bacillus anthracis str. Ames, complete genomeimmune inhibitor A metalloprotease01592
NC_005945:674337:6887766887766911752400Bacillus anthracis str. Sterne, complete genomeimmune inhibitor A metalloprotease01592
NC_007530:674265:6888816888816912802400Bacillus anthracis str. 'Ames Ancestor', complete genomeimmune inhibitor a metalloprotease01592
NC_016779:657568:6702916702916726902400Bacillus cereus F837/76 chromosome, complete genomeImmune inhibitor A, metalloprotease01588
NC_011773:688689:7033197033197057182400Bacillus cereus AH820 chromosome, complete genomeimmune inhibitor A metalloprotease01588
NC_006274:659922:6772146772146796132400Bacillus cereus E33L, complete genomeimmune inhibitor A, metalloprotease01587
NC_005957:667954:6797646797646821632400Bacillus thuringiensis serovar konkukian str. 97-27, completeimmune inhibitor A, metalloprotease01585
NC_016771:701909:7165457165457189442400Bacillus cereus NC7401, complete genomeimmune inhibitor A metalloprotease01576
NC_011969:726369:7381847381847405832400Bacillus cereus Q1 chromosome, complete genomeimmune inhibitor a, metalloprotease01571
NC_011725:681387:6928156928156952142400Bacillus cereus B4264 chromosome, complete genomeimmune inhibitor A metalloprotease01543
NC_017208:671128:6848936848936872922400Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeimmune inhibitor A precursor01542
NC_004722:650950:6623776623776647762400Bacillus cereus ATCC 14579, complete genomeImmune inhibitor A precursor01541
NC_011772:647778:6607236607236631222400Bacillus cereus G9842, complete genomeimmune inhibitor A metalloprotease01538
NC_010184:661226:6739306739306763202391Bacillus weihenstephanensis KBAB4, complete genomepeptidase M6 immune inhibitor A01500
NC_011773:1277606:1305990130599013083772388Bacillus cereus AH820 chromosome, complete genomeimmune inhibitor A metalloprotease InhA101091
NC_014391:421547:4280514280514304682418Micromonospora aurantiaca ATCC 27029 chromosome, complete genomeM6 family metalloprotease domain-containing protein5e-67256
NC_015588:2939747:2958554295855429608692316Isoptericola variabilis 225 chromosome, complete genomeM6 family metalloprotease domain protein2e-62241
NC_014391:421547:4308104308104336022793Micromonospora aurantiaca ATCC 27029 chromosome, complete genomeM6 family metalloprotease domain-containing protein2e-51204
NC_004605:741000:7445507445507476123063Vibrio parahaemolyticus RIMD 2210633 chromosome II, completehypothetical protein2e-0861.6
NC_014966:638355:6418456418456457053861Vibrio vulnificus MO6-24/O chromosome II, complete sequencehypothetical protein1e-0655.8
NC_005140:660305:6637946637946676543861Vibrio vulnificus YJ016 chromosome II, complete sequencehypothetical protein4e-0653.9
NC_004460:81687:8528785287890363750Vibrio vulnificus CMCP6 chromosome II, complete sequencehypothetical protein4e-0653.9